Transparent Graphene via Fermentation for Cancer Therapy

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Solution Overview

Problem

Current methods for producing graphene do not effectively create transparent, antibacterial graphene that can be used to treat cancer without harming human cells.

Innovation Solution

A method involving fermentation of graphene powders with yeast and warm water, followed by multiple steps of fermentation and refinement to produce transparent graphene containing probiotics, which includes heating raw materials to high temperatures, mixing with edible powders and sugars, and repeated drying and soaking processes.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If conventional methods are used to produce graphene, then graphene can be obtained, but it lacks transparency and effective antibacterial properties for cancer treatment

Engineering Contradiction:
Improveantibacterial effectivenessVSAvoidproduction method complexity
Core Design Contradiction:
ReliabilityVSEase of manufacture

Solution Approach 1:

The patent changes the production parameters by using fermentation processes with yeast and probiotics instead of conventional chemical methods. This transforms the graphene production from a simple heating process to a multi-stage biological fermentation process that occurs at lower temperatures (38-40°C) over extended periods (3-7 days), thereby achieving transparency and antibacterial properties while maintaining manufacturing feasibility

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent creates a composite material by combining graphene with probiotics and yeast during the fermentation process. This results in transparent graphene that contains beneficial microorganisms, providing both the structural properties of graphene and the biological activity of probiotics, thereby achieving enhanced antibacterial effectiveness for cancer treatment

Inventive Principle:
Principle #40Composite materials

2Illumination intensity

If graphene is made transparent through fermentation, then antibacterial properties are achieved, but the production process becomes complex with multiple steps

Engineering Contradiction:
ImprovetransparencyVSAvoidnumber of processing steps
Core Design Contradiction:
Illumination intensityVSDevice complexity

Solution Approach 1:

The patent merges multiple functions into a single fermentation process. By combining yeast fermentation with probiotic cultivation in the same process sequence, the method achieves both transparency development and antibacterial property enhancement simultaneously, reducing the need for separate processing steps while maintaining product quality

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The patent implements continuous useful action by maintaining fermentation conditions throughout the entire production process. The graphene is continuously exposed to probiotics and controlled temperature (38-40°C) for extended periods (3-7 days), allowing the transparency and antibacterial properties to develop progressively without interruption, thereby achieving the desired optical and biological properties through sustained biological activity

Inventive Principle:
Principle #20Continuity of useful action

3Reliability

If graphene oxide is used to inhibit cancer cell growth, then treatment effectiveness is improved, but it may harm normal human cells

Engineering Contradiction:
Improvecancer treatment effectivenessVSAvoiddamage to human cells
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent converts the potentially harmful effects of conventional graphene oxide into beneficial properties by using probiotic fermentation. The fermentation process transforms the graphene structure to be transparent and selectively antibacterial, converting the broad-spectrum toxicity of traditional graphene oxide into targeted antibacterial activity that spares human cells while effectively combating cancer cells

Inventive Principle:
Principle #22Blessing in disguise (Convert harm into benefit)

Solution Approach 2:

The patent applies local quality by making the graphene transparent with selective antibacterial properties. The transparent graphene produced through fermentation exhibits localized biological activity that targets cancer cells specifically while leaving normal human cells unharmed, creating a material with spatially differentiated properties that enable selective action against different cell types

Inventive Principle:
Principle #3Local quality

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Results in transparent graphene with antibacterial properties that does not damage human cells, effectively inhibiting cancer cell growth and relieving discomfort.

Implementation Method 1

a method of making graphene transparent by fermentation which is configured to produce transparent graphene containing probiotics

Methodology Applied
Scientific EffectFermentation: Fermentation

Implementation Method 2

heating raw materials configured to produce graphene two times to produce graphene powders, the raw materials are heated to a temperature of 800° C. and are heated again to a temperature of 1000° C.

Methodology Applied
Scientific EffectPyrolysis: Pyrolysis

Implementation Method 3

the holding tray is put into the temperature control room to be dried for multiple days, thus forming graphene enzyme lump

Methodology Applied
Scientific EffectEvaporation: Evaporation

Data Source

PatentUS20240360479A1Method of making graphene transparent by fermentation
Publication Date: 2024.10.31 LI ZHI MIN
  • US20240360479A1 patent drawing
  • US20240360479A1 patent drawing
  • US20240360479A1 patent drawing

AI summary

A method of making graphene transparent by fermentation contains: a step of preparing prerequisites; a first step in which the graphene mother bacteria, edible powders, powdered sugars, and a warm water and mixed and heated to produce a fermented graphene lump; a second step in which fermented graphene lump is smashed and smoothed out to a holding tray, then the holding tray is dried to form graphene enzyme lump. The method further contains: a third step in which the graphene enzyme lump is refined to graphene enzyme powders by a stirrer; a fourth step in which re-fermenting the graphene enzyme powders of the third step by repeating the first step, the second step and the third step; a fifth step in which the re-fermented graphene powders are soaked to produce edible powders, and the warm water is removed; a step sixth in which a transparent graphene containing probiotics is produced.