Tri-leaflet Prosthetic Valve Stent Weaving

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

Current prosthetic heart valves require lifelong anticoagulation therapy due to the risk of thromboembolism or are prone to degeneration and tissue failure, necessitating reoperation.

Innovation Solution

A transcatheter prosthetic heart valve with a stent frame and a tube of leaflet material that encircles the stent frame, featuring a unique geometric design allowing for improved durability and reduced need for sutures, using polymeric or bioprosthetic materials to minimize thrombosis and enhance coaptation, with a self-expandable or balloon-expandable stent frame.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If mechanical or bioprosthetic valves are used in aortic heart valve replacement procedures, then the valve replacement function is achieved, but the patient requires lifelong anticoagulation therapy or becomes prone to valve degeneration and tissue failure

Engineering Contradiction:
Improvevalve durabilityVSAvoidthromboembolism risk
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent changes the material parameters of the valve by using polymeric materials with specific properties (biocompatibility, thromboresistance) to create a valve that eliminates the need for anticoagulation therapy while maintaining durability. The continuous tube structure with specific geometric parameters also contributes to reduced thrombosis risk.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent employs composite material construction by combining polymeric materials with specific functional properties to create a valve that integrates both structural durability and thromboresistance in a single material system, eliminating the need for separate anticoagulation management.

Inventive Principle:
Principle #40Composite materials

2Reliability

If traditional prosthetic heart valves are used, then valve replacement is achieved, but reoperation is required due to valve degeneration and tissue failure

Engineering Contradiction:
Improvevalve longevityVSAvoidvalve service life
Core Design Contradiction:
ReliabilityVSDuration of action of stationary object

Solution Approach 1:

The patent utilizes polymeric materials with enhanced mechanical properties and resistance to degeneration, changing the material parameters to achieve superior longevity and durability compared to traditional bioprosthetic valves, thereby extending the valve's service life and reducing reoperation needs.

Inventive Principle:
Principle #35Parameter changes

3Reliability

If a tube of leaflet material encircles the stent frame with upper portion disposed within the stent frame, then improved durability and reduced suture requirements are achieved, but the manufacturing complexity increases

Engineering Contradiction:
Improveleaflet durabilityVSAvoidvalve assembly difficulty
Core Design Contradiction:
ReliabilityVSEase of manufacture

Solution Approach 1:

The patent merges the leaflet material and stent frame into an integrated structure where the continuous tube of leaflet material encircles and is disposed within the stent frame, eliminating the need for separate suturing operations and reducing assembly complexity despite the sophisticated geometric configuration.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The leaflet material is pre-configured into a continuous tube with specific geometric features before assembly, with the upper portion pre-disposed within the stent frame configuration, allowing for simplified final assembly without requiring complex suturing operations during the implantation procedure.

Inventive Principle:
Principle #10Preliminary action

Data Source

PatentEP3644904B1Prosthetic heart valve with tri-leaflet design for use in percutaneous valve replacement procedures
Publication Date: 2025.01.01 OHIO STATE INNOVATION FOUND
  • EP3644904B1 patent drawingFigure 1
  • EP3644904B1 patent drawingFigure 2
  • EP3644904B1 patent drawingFigure 3~4

AI summary

A transcatheter prosthetic heart valve includes a stent frame and at least one sheet of leaflet material formed in to a tube, which includes a lower portion disposed on an exterior of the stent frame and an upper edge portion disposed within the stent frame. The upper edge portion includes at least a portion configured to wrap around a first portion of the top edge of the stent frame and fold towards an exterior of the stent frame. The upper edge portion also includes at least another portion configured to weave through the stent frame and fold towards the interior of the stent frame.