Trialkyl Gallium Preparation via Ionic Liquid Transalkylation

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Solution Overview

Problem

Existing methods for preparing trialkyl gallium and indium compounds suffer from poor conversions, difficulty in purification, and incomplete transfer of alkyl groups, leading to impurities and contamination issues, which are critical for high-purity semiconductor materials used in vapor deposition techniques.

Innovation Solution

The method involves adding trialkyl aluminum to a mixture of gallium or indium trihalide with a halide salt of a monovalent metal in an ionic liquid solvent, such as a molten salt of the formula M[AlRnX(4-n)], allowing for efficient transfer of at least two alkyl groups and achieving high yield and purity without organic solvents.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of manufacture

If Grignard reagent or alkyl lithium is used in ether or hydrocarbon solvent, then trialkyl gallium or indium compounds can be prepared, but the solvent tightly complexes with the product making separation extremely difficult

Engineering Contradiction:
Improvepreparation of trialkyl metal compoundsVSAvoidseparation and purification
Core Design Contradiction:
Ease of manufactureVSEase of operation

Solution Approach 1:

The patent introduces an alkali metal halide (MX) as an intermediary substance that forms a complex with the trialkyl metal compound. This complexation allows the product to be separated from the reaction mixture by filtration, solving the separation difficulty caused by solvent-product complexation in traditional methods

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent changes the physical state and solubility parameters by using an ionic liquid solvent system with specific alkali metal halides. This creates a system where the product complex is insoluble and can be easily filtered, transforming a difficult liquid-liquid separation into a simple solid-liquid filtration process

Inventive Principle:
Principle #35Parameter changes

2Productivity

If transalkylation is performed with trialkyl aluminum and gallium trihalide, then trialkyl gallium can be formed, but incomplete transfer of alkyl groups results in mixture of products

Engineering Contradiction:
Improveformation of trialkyl galliumVSAvoidpurity of product
Core Design Contradiction:
ProductivityVSManufacturing precision

Solution Approach 1:

The patent employs a catalytic cycle where the alkali metal halide catalyst is regenerated and reused. The catalyst facilitates alkyl group transfer, becomes temporarily consumed, then is regenerated in subsequent steps, creating a feedback loop that drives complete conversion and prevents accumulation of intermediate products

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The patent utilizes phase transition differences between the ionic liquid solvent (which remains liquid at reaction temperature) and the product complex (which precipitates as solid). This phase separation allows complete reaction proceeds while the solid product complex can be easily removed, ensuring high purity

Inventive Principle:
Principle #36Phase transitions

3Productivity

If excess trialkyl aluminum is added to gallium trihalide, then alkyl transfer can be driven to completion, but large excess is needed due to partial transfer

Engineering Contradiction:
Improveconversion of gallium trihalideVSAvoidconsumption of trialkyl aluminum
Core Design Contradiction:
ProductivityVSLoss of substance

Solution Approach 1:

The alkali metal halide catalyst enables the system to be self-sufficient by facilitating complete alkyl transfer without requiring large excesses of reactants. The catalyst activates the gallium trihalide and promotes efficient alkyl group transfer, allowing stoichiometric or near-stoichiometric amounts of trialkyl aluminum to achieve complete conversion

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The patent changes the reaction mechanism by introducing the ionic liquid and alkali metal halide catalyst system, which alters the activation energy and reaction pathway. This enables complete alkyl transfer with near-stoichiometric reagent ratios, transforming a process that required large excesses into an efficient catalytic process

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach results in trialkyl gallium and indium compounds with excellent purity and high yield, reducing contamination and improving the efficiency of the transfer process, suitable for ultra-high purity semiconductor materials.

Implementation Method 1

combining a gallium or indium trihalide with a halide salt of a monovalent metal in an ionic liquid solvent

Methodology Applied
Scientific EffectDissolution: Solvation

Implementation Method 2

addition of trialkyl aluminum to a mixture formed by combining a gallium or indium trihalide with a halide salt... allowing for efficient transfer of at least two alkyl groups

Methodology Applied
Scientific EffectTransalkylation: Chemical Bonding

Implementation Method 3

The desired trialkyl gallium or indium compound is isolated from the reaction mixture by distillation

Methodology Applied
Scientific EffectHeating: Heating

Implementation Method 4

The desired trialkyl gallium or indium compound is isolated from the reaction mixture by distillation

Methodology Applied
Scientific EffectDistillation: Distillation

Data Source

PatentEP2809676B1Preparation of tri-alkyl gallium or tri-alkyl indium compounds
Publication Date: 2016.01.13 CHEMTURA CORP

AI summary

TrialkyI metal compounds, such as trialkyl gallium and indium compounds, are prepared in high yield and high purity by the addition of a trialkyl aluminum compound to a mixture prepared by adding a metal trihalide, e.g., GaCI3 or lnCI3, and a halide salt of a monovalent metal to an ionic liquid such as a molten salt of the formula M[AIRn Chi(4-n)] wherein M is a monovalent metal such as Li, Na, K or Cs, R is an alkyl group X is a halide and n is a number from 1 to 3, typically at temperatures of from 75 to 160° C.