Trichoderma Viride Filtrate Formulation for Stable Pathogen Control

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Solution Overview

Problem

The prevalence of pesticide-resistant pathogens and health issues from chemical fungicides necessitate the development of biological fungicides that maintain vitality and effectiveness over time, while also promoting plant growth.

Innovation Solution

A biocontrol formulation comprising a Trichoderma viride filtrate and inert substances like flour and clay, which includes conidia and fermentation byproducts such as organic acids and amino acids, providing stability and efficacy against fungal pathogens and enhancing plant growth.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If chemical fungicides are used to combat plant pathogens, then pathogen control effectiveness is improved, but health problems and pesticide resistance develop

Engineering Contradiction:
Improvepathogen control effectivenessVSAvoidhealth problems and pesticide resistance
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent replaces chemical fungicides with a biological system using Trichoderma viride fungus and its metabolites to control plant pathogens. The formulation uses natural biological mechanisms (antibiosis, mycoparasitism, induction of systemic resistance) instead of chemical mechanisms, thereby maintaining pathogen control effectiveness while eliminating health problems and resistance issues associated with chemical fungicides.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent introduces Trichoderma viride filtrate and its metabolites as intermediary substances that mediate between the plant and pathogen interaction. These biological intermediaries produce antifungal compounds and stimulate plant defense mechanisms, providing an alternative to direct chemical fungicide application while achieving pathogen control.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Object-affected harmful factors

If microorganisms are used for biocontrol, then health safety is improved, but vitality and activity are lost over time

Engineering Contradiction:
Improvehealth safetyVSAvoidvitality and activity duration
Core Design Contradiction:
Object-affected harmful factorsVSDuration of action of stationary object

Solution Approach 1:

The patent extracts the active metabolites and filtrate from the Trichoderma viride fungus, separating the beneficial biological activity from the living organism itself. This extraction allows the active components (antibiotics, enzymes, growth regulators) to be formulated in a stable form that retains biological activity and health safety benefits without the limitations of live microorganism storage and viability.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent changes the physical and chemical parameters of the biocontrol agent by using filtrate and metabolites instead of whole living fungi. This parameter change transforms the product into a stable formulation that can be stored and applied effectively, maintaining biological activity while improving shelf life and ease of use compared to live microorganism-based products.

Inventive Principle:
Principle #35Parameter changes

3Reliability

If biocontrol formulations are used, then pathogen resistance is avoided, but stability during storage is reduced

Engineering Contradiction:
Improvepathogen resistance avoidanceVSAvoidstorage stability
Core Design Contradiction:
ReliabilityVSStability of the object's composition

Solution Approach 1:

The patent creates a composite formulation combining Trichoderma viride filtrate with inert carriers and stabilizing agents. This composite structure protects the sensitive biological metabolites during storage while maintaining their biocontrol activity. The formulation integrates multiple components (filtrate, carriers, adjuvants) that work together to enhance both storage stability and pathogen control effectiveness.

Inventive Principle:
Principle #40Composite materials

Solution Approach 2:

The patent uses a formulation approach that prioritizes effective delivery of biocontrol agents over long-term stability of the entire product. The formulation is designed for optimal performance during the application window, using stable inert carriers and protective agents that maintain adequate stability during storage and application without requiring the entire formulation to be highly stable over extended periods.

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The formulation effectively inhibits pathogenic fungi, enhances plant growth, and improves soil quality, offering a sustainable and safe alternative to chemical pesticides with reduced application frequency and environmental impact.

Implementation Method 1

a biocontrol formulation including endophytic Trichoderma for combatting fungal pathogens

Methodology Applied
Scientific EffectBiological control:

Implementation Method 2

the filtrate includes conidia of the Trichoderma viride virus and fermentation byproducts of the fungus

Methodology Applied
Scientific EffectFermentation: Fermentation

Data Source

PatentUS12628831B2Biocontrol formulation for controlling plant pathogens
Publication Date: 2026.05.19 KING SAUD UNIVERSITY
  • US12628831B2 patent drawing
  • US12628831B2 patent drawing
  • US12628831B2 patent drawing

AI summary

A biocontrol formulation for plant pathogens includes a Trichoderma viride filtrate and an inert substance selected from the group consisting of a viscosity reducer, a surfactant, flour, clay, and combinations thereof. In an embodiment, the filtrate includes conidia of the Trichoderma viride. In an embodiment, the filtrate includes byproducts obtained from the fermentation of Trichoderma viride. In an embodiment, the byproducts include at least one of the organic acids, growth regulators, and amino acids.