Trifluenfuronate Formulations for Cross-Resistance-Free Pest Control
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Solution Overview
Problem
The growing resistance, resurgence, and residue (3R) problem of agricultural pest insects and mites to chemical agents necessitates the development of a safe and efficient insecticidal and acaricidal agent without cross-resistance.
Innovation Solution
Trifluenfuronate is used as an active ingredient in insecticidal and acaricidal agents to inhibit egg-laying by female pests, prevent egg hatching, and kill adult and nymph stages of agricultural pest insects and mites, formulated into various agricultural acceptable forms.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If chemical agents are continuously used for controlling agricultural pest insects and mites, then the control efficiency is maintained, but the 3R problem (resistance, resurgence, and residue) worsens
Solution Approach 1:
The patent introduces trifluenfuronate, a novel chemical compound with different molecular structure and properties from existing agents. This parameter change in chemical composition provides a new mechanism of action that overcomes resistance developed to previous chemicals, thereby maintaining control efficiency while avoiding the 3R problems associated with continuous use of conventional agents
Solution Approach 2:
The patent formulates trifluenfuronate in combination with various adjuvants and carriers to create composite insecticidal and acaricidal preparations. These composite formulations enhance the efficacy and stability of the active ingredient while reducing the required dosage and minimizing residue, thus addressing the 3R problem while maintaining reliable pest control
2Object-affected harmful factors
If a novel insecticidal and acaricidal agent without cross-resistance is developed, then the 3R problem is solved, but the safety and efficiency requirements must be met simultaneously
Solution Approach 1:
The patent employs trifluenfuronate as a single-use active ingredient in formulated preparations that are applied directly to crops. The compound acts quickly to eliminate pests and then degrades, providing a disposable solution that prevents resistance buildup while maintaining high efficiency and safety profiles through its specific mode of action and favorable toxicological properties
Solution Approach 2:
The patent optimizes the concentration, purity, and formulation parameters of trifluenfuronate to achieve the desired balance between safety and efficiency. By precisely controlling these parameters in the final product, the patent ensures that the novel agent meets both the no-cross-resistance requirement and the safety-efficiency standards for agricultural use
Data Source
AI summary
Trifluenfuronate is used for the prevention and treatment of agricultural pest insects and mites. The trifluenfuronate can be configured as an agriculturally allowable emulsifiable concentrate, aqueous emulsion, aqueous solution, wettable powder, microemulsion, suspension, capsule suspension, or water dispersible granule, wherein the content of the trifluenfuronate in the dosage form is 1-80%. The trifluenfuronate has an outstanding effectiveness of control of agricultural pest insects and mites, and trifluenfuronate is a new compound, and there is no cross-resistance with existing products.