Triple Polymer Fluoride System for Dental Erosion Protection

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Solution Overview

Problem

Current oral care compositions are inadequate in preventing dental erosion and tooth wear, as they fail to effectively enhance the efficacy of fluoride ions in combating these issues, despite the presence of polymers like xanthan gum and carboxymethyl cellulose, which are known to provide some protection against demineralization.

Innovation Solution

A triple polymer system comprising xanthan gum, carboxymethyl cellulose, and copovidone, in conjunction with a source of fluoride ions, is used to enhance fluoride retention at the tooth surface, increasing remineralization and acid resistance, thereby providing better protection against dental erosion and tooth wear.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If fluoride ions are used alone to combat dental erosion, then some protection against demineralization is provided, but the efficacy is insufficient to fully prevent tooth wear and erosion

Engineering Contradiction:
Improveprotection efficacy against dental erosionVSAvoidtooth wear and demineralization
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent combines fluoride ions with a triple polymer system (xanthan gum, carboxymethyl cellulose, and copovidone) to create a composite oral care composition. This composite approach allows the polymers to form a protective matrix that enhances fluoride retention and delivery to the tooth surface, thereby improving the overall reliability of protection against dental erosion beyond what fluoride alone can achieve.

Inventive Principle:
Principle #40Composite materials

Solution Approach 2:

The triple polymer system acts as an intermediary between the fluoride ions and the tooth surface. The polymers form a protective layer that facilitates fluoride adhesion and controlled release, enhancing the effectiveness of fluoride in preventing demineralization and tooth wear without directly providing protection themselves.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Reliability

If polymers like xanthan gum and carboxymethyl cellulose are added to enhance protection, then some improvement in demineralization resistance is achieved, but the overall protection against tooth wear remains inadequate

Engineering Contradiction:
Improvedemineralization resistanceVSAvoidtooth wear susceptibility
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent merges three different polymers (xanthan gum, carboxymethyl cellulose, and copovidone) with fluoride ions in a single oral care composition. This combination creates synergistic effects where each polymer contributes unique properties that collectively enhance both demineralization resistance and tooth wear protection, achieving comprehensive protection that neither polymers nor fluoride alone can provide.

Inventive Principle:
Principle #5Merging (Combining)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The triple polymer system significantly increases the effectiveness of fluoride ions in preventing dental erosion and tooth wear, re-hardening enamel, and reducing susceptibility to acid-mediated damage, while also combating dental caries.

Implementation Method 1

The triple polymer system helps retain fluoride at the tooth surface thereby increasing the remineralisation of teeth

Methodology Applied
Scientific EffectAdsorption: Adsorption

Implementation Method 2

the triple polymer system helps retain fluoride at the tooth surface thereby increasing the remineralisation of teeth and increasing the acid resistance of teeth, so providing a better surface protection against the effects of dental erosion

Methodology Applied
Scientific EffectPhysical barrier formation: Coatings

Data Source

PatentEP2373280B1Novel use
Publication Date: 2017.05.10 GLAXOSMITHKLINE CONSUMER HEALTHCARE (UK) IP LTD
  • EP2373280B1 patent drawingFigure 1a~1b
  • EP2373280B1 patent drawing
  • EP2373280B1 patent drawing

AI summary

A oral care composition comprising a triple polymer system and a source of fluoride ions for combating (i.e. helping to prevent, inhibit and/or treat) dental erosion and/or tooth wear is described. Such compositions are also of use in combating dental caries.