TRP Channel Activator Compositions for Exercise Performance

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Solution Overview

Problem

Athletes seek nutritional ergogenic aids to maintain optimal physical performance and mental function during exercise and enhance recovery, but existing solutions are inadequate in improving exercise performance and recovery.

Innovation Solution

Compositions comprising activators of TRP and ASIC channels, such as capsaicinoids, gingerols, or cinnamaldehyde, administered orally in beverages to improve or preserve exercise performance and recovery by reducing fatigue, pain, and inflammation.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If traditional nutritional ergogenic aids are used, then athletes attempt to maintain optimal physical performance, but existing solutions are inadequate in improving exercise performance and recovery

Engineering Contradiction:

Improveexercise performanceVSAvoidrecovery enhancement

Core Design Contradiction:

ReliabilityVSAdaptability or versatility

Solution Approach 1:

The composition combines multiple TRP channel activators (capsaicinoid, gingerol, cinnamaldehyde) in a single formulation that simultaneously addresses both exercise performance enhancement and recovery improvement, making the product universally effective for both functions rather than requiring separate interventions

Inventive Principle:

Principle #6Universality (Multi-functionality)

2Productivity

If TRP channel activators are administered to improve exercise performance, then exercise completion time is shortened and maximal oxygen consumption increases, but the mechanisms of action are complex and not fully understood

Engineering Contradiction:

Improveexercise completion speedVSAvoidmechanism understanding

Core Design Contradiction:

ProductivityVSDifficulty of detecting and measuring

Solution Approach 1:

The invention segments the complex physiological response into distinct measurable outcomes (exercise completion time, maximal oxygen consumption, fatigue levels, perceived exertion) and attributes them to specific TRP channel activators, making the mechanisms more detectable and measurable through controlled experimentation

Inventive Principle:

Principle #1Segmentation

3Reliability

If TRP channel activators are used to decrease fatigue and pain, then exercise performance is improved, but the compositions require precise formulation with multiple components

Engineering Contradiction:

Improvefatigue reductionVSAvoidcomposition formulation

Core Design Contradiction:

ReliabilityVSDevice complexity

Solution Approach 1:

The invention merges multiple TRP channel activators (capsaicinoid, gingerol, cinnamaldehyde) into a single synergistic composition that achieves reliable fatigue and pain reduction through combined action, simplifying the formulation process while maintaining effectiveness

Inventive Principle:

Principle #5Merging (Combining)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The compositions effectively shorten exercise completion time, increase maximal oxygen consumption, decrease fatigue, improve energy and mood, and reduce perceived exertion and pain, while also reducing exercise-induced inflammation.

Implementation Method 1

compositions comprising activators of TRP and ASIC channels, such as capsaicinoids, gingerols, or cinnamaldehyde, administered orally in beverages to improve or preserve exercise performance and recovery by reducing fatigue, pain, and inflammation

Methodology Applied

Scientific EffectTRP channel activation:

Data Source

PatentUS11253493B2Compositions and methods affecting exercise performance

Publication Date: 2022.02.22 CLIFF CARTWRIGHT CORP

AI summary

Described herein are compositions comprising activators of TRP and ASIC channels that may be useful to improve or preserve exercise performance and exercise recovery.