Inspection Assistance Device for Tumor Content Analysis

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Solution Overview

Problem

The high computational cost of identifying regions with high tumor cell content rates in pathological images for genetic panel tests, as existing methods process entire images, leading to inefficient calculation processes.

Innovation Solution

An inspection assistance device and system that acquires pathology specimen images, allows region designation, detects tumor and non-tumor cell positions, and calculates tumor cell content rates for divided regions of predetermined sizes, reducing the computational burden by focusing on specific areas.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If processing is performed on the entire pathology specimen image, then the identification of tumor cell content rate is comprehensive, but the calculation cost becomes high

Engineering Contradiction:
Improvetumor cell content rate identification accuracyVSAvoidcalculation cost
Core Design Contradiction:
Measurement precisionVSUse of energy by stationary object

Solution Approach 1:

The pathology specimen image is divided into multiple divided regions, and tumor cell content rate calculation is performed separately for each divided region. This segmentation approach reduces the computational burden of processing the entire image while maintaining comprehensive identification of tumor cell distribution across different areas of the specimen.

Inventive Principle:
Principle #1Segmentation

2Reliability

If the entire image is processed to identify tumor regions, then complete coverage is achieved, but the processing time increases

Engineering Contradiction:
Improveregion identification completenessVSAvoidprocessing time
Core Design Contradiction:
ReliabilityVSLoss of time

Solution Approach 1:

The image is segmented into multiple divided regions that are processed independently and in parallel. This segmentation enables complete coverage of the entire pathology specimen while reducing processing time through parallel computation across multiple regions.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The system calculates tumor cell content rates for divided regions rather than processing the entire image as a single unit. This partial action approach maintains reliability by covering all necessary areas while reducing the time cost through manageable regional processing.

Inventive Principle:
Principle #16Partial or excessive action

Data Source

PatentUS20240303807A1Inspection assistance device, inspection assistance method, and recording medium
Publication Date: 2024.09.12 NEC CORP
  • US20240303807A1 patent drawing
  • US20240303807A1 patent drawing
  • US20240303807A1 patent drawing

AI summary

Provided is a technology for reducing calculation cost for identifying a region that has a high tumor content ratio and is used for gene panel testing. This testing support device comprises an acquisition means that acquires a pathological specimen image, a region reception means that receives designation of a region for the acquired pathological specimen image, a detection means that detects the position of a tumor cell and the position of a non-tumor cell in the designated region of the pathological specimen image, and a calculation means that calculates a tumor content ratio for each divided region, which is obtained through division a predetermined size, on the basis of the detected position of a tumor cell and the detected position of a non-tumor cell.