Phased Array Tumor Marker Localization With Adaptive Impedance Matching

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Solution Overview

Problem

Current systems for real-time tumor positioning in radiation therapy face challenges such as limited field of view, high electromagnetic radiation exposure to patients, and inefficiencies due to antenna impedance mismatch, particularly for patients with large body sizes and during radiotherapy.

Innovation Solution

A phased array antenna system with a processor that transmits and receives wireless signals to implanted markers, using adaptive impedance matching and a ferromagnetic layer to reduce EM radiation exposure and improve tracking accuracy, while allowing for precise localization of tumors.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If a wireless transceiver is placed on top of the patient to track tumor location, then millimeter range accuracy is achieved, but the system blocks the beam path during radiotherapy and exposes the patient to significantly high EM radiation

Engineering Contradiction:
Improvetumor tracking accuracyVSAvoidEM radiation exposure
Core Design Contradiction:
Measurement precisionVSObject-affected harmful factors

Solution Approach 1:

The patent extracts the tracking function from an active transceiver system and implements it using a passive RFID tag system. The passive tag is implanted near the tumor and can be tracked by external readers without requiring an active transmitter in the patient's body, thereby eliminating the blocking issue and reducing EM radiation exposure while maintaining millimeter-level tracking accuracy

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent introduces a ferromagnetic layer as an intermediary component between the antenna and the patient's body. This layer focuses and directs the EM field toward the implant site, improving coupling efficiency with the passive RFID tag while reducing the overall EM radiation dose required for tracking, thus addressing both the accuracy and radiation exposure concerns

Inventive Principle:
Principle #24Intermediary (Mediator)

2Measurement precision

If a wireless transceiver is placed on top of the patient to track tumor location, then millimeter range accuracy is achieved, but navigation volume is limited by the generated magnetic field and usage is limited for patients with large body size

Engineering Contradiction:
Improvetumor tracking accuracyVSAvoidapplicability to large patients
Core Design Contradiction:
Measurement precisionVSAdaptability or versatility

Solution Approach 1:

By extracting the active transmission function from the implanted device and placing it in external readers, the system eliminates the magnetic field generation limitation. The passive RFID tags can be tracked over larger volumes and distances without the constraints of a limited onboard power source and magnetic field range, making the system suitable for patients with large body sizes

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent uses multiple external antenna elements that can be selectively activated to create virtual antenna positions. This allows the system to electronically steer and expand the navigation volume without physically moving or reconfiguring the implanted passive tag, enabling tracking across larger patient anatomies while maintaining millimeter-level accuracy

Inventive Principle:
Principle #26Copying

3Measurement precision

If a wireless transceiver is placed on top of the patient to track tumor location, then tumor positioning is achieved, but lots of EM energy is wasted due to antenna impedance mismatch

Engineering Contradiction:
Improvetumor localization capabilityVSAvoidEM energy waste
Core Design Contradiction:
Measurement precisionVSLoss of energy

Solution Approach 1:

The ferromagnetic layer acts as an intermediary that focuses and directs the EM field energy toward the implant site. This improves the coupling efficiency between the external antenna and the passive RFID tag, reducing energy loss due to impedance mismatch and minimizing wasted EM energy while maintaining effective tracking capability

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent employs adjustable impedance matching circuits and reconfigurable antenna elements that can adapt their electrical parameters to optimize coupling with the passive RFID tag. By dynamically adjusting impedance parameters, the system minimizes energy loss due to mismatch while maintaining accurate tumor localization capability

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The system effectively reduces EM radiation exposure and improves tracking accuracy for tumor localization, accommodating larger patients and minimizing beam path interference during radiotherapy.

Implementation Method 1

the processor is configured to determine a location of the wireless marker based on a time of flight of the transmitted and received wireless signals

Methodology Applied
Scientific EffectTime of flight: Time of Flight

Implementation Method 2

a ferromagnetic layer to reduce EM radiation exposure and improve tracking accuracy

Methodology Applied
Scientific EffectFerromagnetism: Ferromagnetism

Data Source

PatentUS12053245B2Apparatus and method for real-time object monitoring
Publication Date: 2024.08.06 MEDICAL INTELLIGENCE MEDIZINTECHN GMBH
  • US12053245B2 patent drawing
  • US12053245B2 patent drawing
  • US12053245B2 patent drawing

AI summary

The present disclosure provides an apparatus for determining a location of a wireless marker for a tumor, the apparatus comprising: a phased array antenna, and a processor, wherein the processor is configured to control the phased array antenna to transmit a wireless signal to the wireless marker, receive a wireless signal transmitted by the wireless marker in response to the transmitted wireless signal, and analyze the wireless signals transmitted and received by the phased array antenna to determine a location of the wireless marker. The present disclosure also provides a method for determining a location of a wireless marker for a tumor, wherein the method comprises: transmitting, using a phased antenna array, a wireless signal to the wireless marker, receiving, at the phased antenna array, a wireless signal transmitted by the wireless marker in response to the transmitted wireless signal, and analyzing the wireless signals transmitted and received by the phased array antenna to determine a location of the wireless marker.