Patient-Specific Tumor Resection Guide Using 3D Tissue Mapping
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Solution Overview
Problem
Existing breast tumor resection surgeries often fail to ensure complete removal of cancerous tissue, leading to the need for additional surgeries and radiation treatment due to challenges in accurately guiding the resection process.
Innovation Solution
A system and method that generates surgical guidance cues based on patient-specific three-dimensional spatial properties, using imaging and registration techniques to create a patient-specific locator form with features indicating surgical guidance cues, aiding in precise tumor resection.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Manufacturing precision
If traditional wire or radio-opaque clip guidance is used for breast tumor resection, then the surgical procedure can be performed, but complete removal of cancerous tissue cannot be ensured leading to residual cancer and need for additional treatments
Solution Approach 1:
The patent transitions from two-dimensional imaging (mammography, ultrasound) to three-dimensional imaging (MRI, CT, 3D mammography) to provide comprehensive spatial information about tumor location, shape, and extent. This dimensional enhancement allows surgeons to visualize and resect the complete tumor perimeter including filaments and fimbriae that extend in multiple directions, ensuring complete removal while preserving healthy tissue.
Solution Approach 2:
The patent creates a virtual 3D model or map of the tumor and surrounding tissue architecture based on preoperative imaging. This digital copy is then used to plan the resection boundaries and guide the surgical procedure, allowing surgeons to visualize the complete tumor extent before making incisions. The virtual model serves as a roadmap to ensure all cancerous tissue is included in the resection margin.
2Productivity
If breast tumor resection is performed to remove cancerous tissue, then the tumor can be removed, but cancerous tissue often remains requiring radiation treatment and additional surgeries
Solution Approach 1:
The patent performs comprehensive preoperative planning including 3D imaging, tumor mapping, and resection boundary determination before the surgical procedure. Virtual reality simulations and physical models are created beforehand to identify the precise extent of tumor infiltration and plan the optimal resection margins. This preliminary action ensures that all cancerous tissue is targeted during surgery, eliminating the need for postoperative radiation or additional corrective surgeries.
3Measurement precision
If imaging guidance is used to locate the tumor, then the tumor position can be identified, but it is challenging to ensure the entire perimeter including filaments and fimbriae is removed
Solution Approach 1:
The patent combines multiple imaging modalities (MRI, CT, 3D mammography, ultrasound) to create a composite 3D representation of the tumor and surrounding tissue. Each imaging modality provides complementary information about tumor characteristics, and their integration creates a comprehensive view of the tumor perimeter including subtle extensions like filaments and fimbriae. This composite approach ensures complete visualization and resection of all cancerous tissue boundaries.
Data Source
AI summary
A patient-specific device for guiding resection of a tumor located in local tissue of a patient includes a locator form and a surgical guidance cue. The locator form has a locator-form surface matching a surface of the local tissue of the patient near the tumor's location when the local tissue is imaged in a preoperative position, such that the locator form, when fit to the surface of the local tissue, restores the local tissue to the preoperative position. The surgical guidance cue is integrally formed with the locator form and based on images including only preoperative images of the local tissue in the preoperative position, to indicate a spatial property of the tumor in the preoperative position.