Ready-to-Use Tumor Screening Kit With Stable Iodine Reagents

The patent applies preliminary action by pre-preparing and packaging stable iodine reagent formulations in ready-to-use containers. Instead of requiring users to extemporaneously prepare unstable iodine solutions from base components, the invention provides pre-formulated reagents that are stable at room temperature and can be directly applied to saliva samples, eliminating the need for specialized laboratory preparation while maintaining diagnostic accuracy for detecting L-fucose in tumor patients

The patent employs disposable single-use reagent containers and test strips that are pre-packaged and discarded after one use. This eliminates the need for specialized equipment and allows any individual to perform the test at home. The disposable nature ensures reagent stability and prevents contamination, making the tumor diagnosis method both accurate and easily operable by non-experts

The patent applies parameter changes by modifying the chemical formulation of the iodine reagent to improve stability. The invention uses specific ratios of iodine to potassium iodide in buffered solutions, and alternatively employs iodine-impregnated solid supports or iodine-releasing compounds that maintain stable iodine activity at room temperature. These formulation changes allow the reagent to remain stable without requiring dark storage or refrigeration, while still providing accurate detection of L-fucose in tumor patients

The patent uses composite material systems combining iodine with stabilizing agents such as potassium iodide, buffers, and protective matrices. The iodine is incorporated into stable composite formulations including iodine-impregnated solid supports, iodine-releasing polymers, or iodine complexes with stabilizing molecules. These composite structures protect the iodine from degradation while maintaining its reactivity with L-fucose, achieving both stability and diagnostic accuracy