Two-Electrode Analyte Sensor Modulated Voltage Potential

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Solution Overview

Problem

Current electrochemical analyte sensors face issues with material wear, chemical leakage, and accuracy degradation due to shifting reference potentials, requiring complex and costly designs with multiple electrodes.

Innovation Solution

A simplified analyte sensor design using a modulated voltage signal between two electrodes to determine an electric potential working point, allowing for stable and drift-free measurements without a dedicated reference electrode, ensuring proportional analyte concentration correlation and reduced interference.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If a modulated voltage signal is applied between two electrodes to determine an electric potential working point, then measurement stability and accuracy are improved, but the device complexity increases due to the need for signal modulation and determination circuitry

Engineering Contradiction:
Improvemeasurement stabilityVSAvoiddevice complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent applies a modulated voltage signal (periodic action) between the two electrodes to determine the electric potential working point. This periodic modulation allows the system to identify the optimal operating point by analyzing the response at different voltage levels, thereby improving measurement stability without requiring additional reference electrodes.

Inventive Principle:
Principle #19Periodic action

Solution Approach 2:

The two-electrode sensor performs self-diagnosis and self-regulation by applying the modulated voltage signal and determining the electric potential working point based on its own response. The sensor automatically identifies its optimal operating conditions without external intervention or additional reference components, enabling it to serve itself in maintaining measurement accuracy.

Inventive Principle:
Principle #25Self-service

2Device complexity

If a simplified two-electrode design is used, then device complexity and manufacturing cost are reduced, but measurement accuracy degrades due to reference potential drift

Engineering Contradiction:
Improvedevice complexityVSAvoidmeasurement accuracy
Core Design Contradiction:
Device complexityVSMeasurement precision

Solution Approach 1:

The patent dynamically determines the electric potential working point by applying a modulated voltage signal and analyzing the current response. This parameter change approach allows the sensor to adaptively find and maintain the optimal operating voltage, compensating for reference potential drift without requiring a traditional three-electrode configuration.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The system implements a feedback mechanism where the current response to the modulated voltage signal is measured and used to determine the electric potential working point. This closed-loop feedback enables the sensor to automatically adjust and maintain accurate measurements despite drift in reference potentials or environmental changes.

Inventive Principle:
Principle #23Feedback

3Measurement precision

If traditional multi-electrode sensors are used, then measurement accuracy is maintained, but material wear and chemical leakage increase

Engineering Contradiction:
Improvemeasurement accuracyVSAvoidmaterial wear
Core Design Contradiction:
Measurement precisionVSLoss of substance

Solution Approach 1:

The patent extracts the reference electrode from the traditional three-electrode configuration, reducing the system to only two working electrodes. By eliminating the separate reference electrode, the sensor reduces material wear and chemical leakage while maintaining measurement accuracy through the modulated voltage signal approach that determines the working point dynamically.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The two electrodes in the patent serve multiple functions: they act as both working electrodes for analyte detection and implicitly as reference electrodes for potential determination. This multi-functionality reduces the number of materials required, minimizing wear and chemical leakage while maintaining the ability to perform accurate measurements.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The solution provides robust, accurate, and reliable analyte measurements by maintaining a stable electric potential working point, eliminating the need for additional electrodes and reducing material wear, while ensuring energy efficiency and compact design.

Implementation Method 1

the first electrode can be configured to electrochemically react with the analyte to be measured for generating an electrical signal

Methodology Applied
Scientific EffectElectrochemical reaction: Electrolysis

Implementation Method 2

applying a modulated voltage signal between the first electrode and the second electrode, determining a current signal in response to the applied modulated voltage signal

Methodology Applied
Scientific EffectOhm's Law: Ohm's Law

Data Source

PatentUS20240230576A1Regulation of a two-electrode analyte sensor
Publication Date: 2024.07.11 ROCHE DIABETES CARE INC
  • US20240230576A1 patent drawing
  • US20240230576A1 patent drawing

AI summary

This disclosure relates to a system, a sensor and a method for measuring an analyte concentration using an electrochemical analyte sensor having first and second electrodes. The first electrode reacts with the analyte for generating an electrical signal. The inventive method includes applying a modulated voltage signal between the first electrode and the second electrode, determining a current signal in response to the applied modulated voltage signal, determining an electric potential working point of the analyte sensor based on the determined current signal, operating the analyte sensor at the determined electric potential working point, and measuring the analyte concentration based on the electrical signal generated by the first electrode.