Two-Electrode Test Strip Mimicking Three-Electrode Functionality

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Solution Overview

Problem

Conventional glucose test sensors require a larger fluid chamber to accurately measure analyte concentrations, which can lead to increased blood volume requirements, causing discomfort and potential inaccuracies due to chamber size limitations, such as vision issues and capillary action inefficiencies.

Innovation Solution

A disposable electrochemical test sensor design featuring a fluid sample chamber with two electrodes that function as three, utilizing potential reversal and curve-fitting technology to mimic the functionality of a three-electrode system, allowing for a shorter chamber length and reduced volume without compromising performance.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Quantity of substance

If the fluid chamber volume is reduced to minimize blood volume requirements, then patient comfort improves and pain from finger piercing is reduced, but the chamber may become too small for effective capillary action and accurate analyte measurement

Engineering Contradiction:
Improveblood volumeVSAvoidmeasurement accuracy
Core Design Contradiction:
Quantity of substanceVSReliability

Solution Approach 1:

The patent combines the functions of three electrodes (working electrode, reference electrode, and blank electrode) into two electrodes by making one electrode multi-functional. The first electrode serves as both working electrode and reference electrode, while the second electrode serves as both blank electrode and reference electrode, allowing the system to maintain measurement accuracy with reduced blood volume

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The patent transitions from a longitudinal arrangement of three electrodes to a configuration where two electrodes perform three functions by utilizing different measurement modes (with enzyme and without enzyme) and mathematical processing, effectively adding a functional dimension rather than a physical one

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

2Length of moving object

If the chamber length is reduced to decrease fluid volume requirements, then sample consumption is minimized, but the chamber may not provide sufficient space for proper fluid flow and electrode functionality

Engineering Contradiction:
Improvechamber lengthVSAvoidcapillary action efficiency
Core Design Contradiction:
Length of moving objectVSProductivity

Solution Approach 1:

The patent merges the functionality of three electrodes into two electrodes, allowing the chamber length to be reduced while maintaining all necessary electrochemical measurement functions through intelligent electrode design and signal processing

Inventive Principle:
Principle #5Merging (Combining)

3Quantity of substance

If the chamber width is reduced to minimize blood volume, then the required blood sample size decreases, but users with vision problems or trembling hands cannot easily locate the opening end

Engineering Contradiction:
Improveblood volumeVSAvoidease of locating opening end
Core Design Contradiction:
Quantity of substanceVSEase of operation

Solution Approach 1:

The patent solves the width reduction problem by transitioning to a two-electrode design that maintains functional equivalence to three electrodes, allowing volume reduction without compromising usability through a different architectural approach rather than simply scaling down all dimensions

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

4Quantity of substance

If the chamber thickness is reduced to minimize blood volume, then the required blood sample size decreases, but capillary action becomes less effective resulting in insufficient or non-continuous filling

Engineering Contradiction:
Improveblood volumeVSAvoidcapillary action effectiveness
Core Design Contradiction:
Quantity of substanceVSSpeed

Solution Approach 1:

The patent combines electrode functions to reduce the number of electrodes from three to two, enabling chamber thickness reduction while maintaining adequate capillary action through optimized chamber geometry and surface properties rather than relying on increased thickness

Inventive Principle:
Principle #5Merging (Combining)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This design significantly reduces the fluid chamber volume while maintaining accurate analyte concentration measurements, minimizing blood volume requirements and ensuring reliable test results.

Implementation Method 1

The chamber is adapted to receive a fluid sample and escape air through capillary action

Methodology Applied
Scientific EffectCapillary action: Capillary Action

Data Source

PatentUS10920259B2Two electrodes functioning as three electrodes in the fluid chamber of a test strip
Publication Date: 2021.02.16 SINOCARE
  • US10920259B2 patent drawing
  • US10920259B2 patent drawing
  • US10920259B2 patent drawing

AI summary

An improved disposable electrochemical test sensor designed to facilitate reducing volume of fluid samples. It has a short fluid chamber having two electrodes that functions as three electrodes (one working electrode, one reference electrode and one blank electrode). The chamber provides a reservoir from which a sample fluid can be quickly drawn into the chamber through capillary action. The novel potential reverse and curve-fitting technology of the test sensor provided by the present invention can effectively eliminate most common interferents existing in the fluid samples.