Ubiquinol Gel Composition Stabilization
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Solution Overview
Problem
The stability and high absorbability of ubiquinol in supplements are compromised due to its instability in air and low water solubility, requiring the use of emulsifiers and oils, which are undesirable for health-conscious consumers, and existing methods fail to provide a stable, high-concentration, water-dispersible form.
Innovation Solution
A gel-like composition is developed containing ubiquinol dispersed in a gel matrix with gelatin, carbohydrate, and/or water-soluble dietary fiber, along with ascorbic acid and gallate-type catechin, which maintains high stability and absorbability without the need for emulsifiers or oils, allowing for a high concentration of ubiquinol in a water-dispersible form.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Quantity of substance
If ubiquinol is blended in high concentration in supplements, then the effectiveness and value of the supplement is improved, but the stability of ubiquinol deteriorates due to oxidation in air
Solution Approach 1:
The patent introduces ascorbic acid and gallate-type catechin as intermediary substances that act as antioxidants to protect ubiquinol from oxidation. These mediators scavenge free radicals and prevent the oxidation of ubiquinol, allowing high concentrations of ubiquinol to be maintained in a stable state without requiring emulsifiers or oils.
Solution Approach 2:
The patent creates a composite formulation combining ubiquinol with ascorbic acid, gallate-type catechin, and other functional ingredients. This composite approach allows the synergistic effects of multiple components to enhance both the stability and bioavailability of ubiquinol, achieving high concentration blending without compromising stability.
2Ease of operation
If emulsifiers and oils are added to improve ubiquinol dispersibility in water, then the water dispersibility is improved, but the product appeals to health-conscious consumers deteriorates due to use of food additives
Solution Approach 1:
The patent extracts and eliminates emulsifiers and oils from the formulation, achieving water dispersibility through alternative mechanisms. The ubiquinol is dispersed in water using natural ingredients like ascorbic acid and gallate-type catechin, which provide dispersibility without requiring synthetic emulsifiers, thus maintaining consumer appeal for natural products.
Solution Approach 2:
The patent uses water-soluble, naturally degradable ingredients instead of persistent emulsifiers. The dispersing agents used are naturally occurring substances that break down easily, providing a temporary dispersing effect that is sufficient for supplementation purposes without leaving harmful residues, aligning with natural product preferences.
3Adaptability or versatility
If ubiquinol is dispersed in water without emulsifiers, then consumer acceptance is improved, but the stability and uniform dispersion of ubiquinol deteriorates
Solution Approach 1:
The patent uses ascorbic acid and gallate-type catechin as intermediary substances that facilitate the dispersion of ubiquinol in water without emulsifiers. These mediators interact with ubiquinol to enhance its water compatibility and prevent aggregation, maintaining stable dispersion in the absence of traditional emulsifying agents.
Solution Approach 2:
The patent changes the chemical parameters of the system by introducing antioxidants that modify the oxidation-reduction environment. This parameter change prevents ubiquinol oxidation and maintains its dispersed state, achieving both consumer acceptance and stability without emulsifiers.
4Stability of the object's composition
If conventional stabilization methods using citric acid and ascorbic acid are used, then some stability is improved, but sufficient stability and uniform water dispersion are not achieved
Solution Approach 1:
The patent combines ascorbic acid with gallate-type catechin and other functional ingredients to create a composite stabilization system. This multi-component approach provides synergistic effects that enhance stability beyond what single ingredients can achieve, ensuring both sufficient stability and uniform water dispersion of ubiquinol.
Solution Approach 2:
The patent uses ingredients like ascorbic acid and gallate-type catechin that perform multiple functions: they act as antioxidants to prevent oxidation, as dispersing agents to maintain uniform distribution, and as stability enhancers to prevent precipitation. This multi-functionality achieves comprehensive stabilization that conventional single-ingredient methods cannot provide.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The gel-like composition ensures long-term storage stability and high absorbability of ubiquinol, enabling a convenient and palatable supplement form that can be taken without water, addressing the limitations of existing methods.
Implementation Method 1
The ubiquinol, however, is likely to be oxidized to ubiquinone due to oxygen and the like in the air, and thus is a very unstable substance... the gel-like composition further contains ascorbic acid and/or gallate type catechin
Implementation Method 2
ubiquinol is dispersed and stabilized in a gel containing 5 to 15% by weight of gelatin, 55 to 80% by weight of carbohydrate and/or water-soluble dietary fiber... the ubiquinol has low solubility in water and thus easily causes crystallization and separation in water
Data Source
AI summary
This invention relates to a gel-like composition in which ubiquinol is dispersed and stabilized in a gel and which contains 0.2 to 5% by weight of ubiquinol, 5 to 15% by weight of gelatin, 55 to 80% by weight of carbohydrate and/or water-soluble dietary fiber, and 9 to 18% by weight of water, and further contains ascorbic acid and/or gallate type catechin.