Ultrafiltration Pump Flow Path Design for Blood Purification

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Solution Overview

Problem

In existing blood purification apparatuses, the ultrafiltration pump is prone to clogging due to waste products like protein flowing through it during ultrafiltration, leading to difficulty in maintaining accurate volume control over time.

Innovation Solution

The ultrafiltration pump is designed to operate such that it draws dialysate from the dialysate introduction line, reducing the volume of dialysate introduced into the blood purification device, thereby preventing waste liquid from flowing through it, and is synchronized with the liquid-delivering pump to ensure efficient ultrafiltration without dialysate backflow.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If the ultrafiltration pump is provided to the bypass line connected to the dialysate drain line, then ultrafiltration can be performed by removing water from blood, but waste liquid containing protein adheres to the pump chamber making it difficult to control ultrafiltration volume over time

Engineering Contradiction:
Improveultrafiltration volume control accuracyVSAvoidwaste liquid adhesion to pump chamber
Core Design Contradiction:
ReliabilityVSObject-generated harmful factors

Solution Approach 1:

The patent extracts the harmful element (waste liquid) from the ultrafiltration pump's flow path by providing a separate drain line that bypasses the pump. The ultrafiltration pump only handles dialysate introduction, while waste liquid is drained through a dedicated line, preventing protein adhesion and maintaining pump performance over time.

Inventive Principle:
Principle #2Taking out (Extraction)

2Object-generated harmful factors

If the ultrafiltration pump draws dialysate from the dialysate introduction line, then waste liquid is prevented from flowing through the pump, but dialysate volume control must be precisely coordinated with the liquid-delivering pump

Engineering Contradiction:
Improvewaste liquid flow through ultrafiltration pumpVSAvoidpump synchronization control
Core Design Contradiction:
Object-generated harmful factorsVSDevice complexity

Solution Approach 1:

The patent uses the dialysate introduction line as an intermediary pathway. The ultrafiltration pump draws dialysate from this line, which serves as a common fluid pathway for both the liquid-delivering pump and ultrafiltration pump. This intermediary approach allows coordinated control while preventing waste liquid contamination.

Inventive Principle:
Principle #24Intermediary (Mediator)

3Ease of operation

If the ultrafiltration pump operates independently without synchronization, then the system is simpler to operate, but dialysate backflow may occur reducing ultrafiltration efficiency

Engineering Contradiction:
Improvepump operation simplicityVSAvoidultrafiltration efficiency
Core Design Contradiction:
Ease of operationVSProductivity

Solution Approach 1:

The patent implements feedback control through the liquid-delivering pump's liquid delivery amount information. The ultrafiltration pump's operation is controlled based on feedback from the liquid-delivering pump's performance, ensuring coordinated operation that prevents backflow while maintaining efficient ultrafiltration.

Inventive Principle:
Principle #23Feedback

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This configuration maintains the performance and accuracy of ultrafiltration over a long period by preventing waste liquid from clogging the ultrafiltration pump and allows for efficient use of dialysate, enabling ultrafiltration without introducing dialysate into the blood purification device.

Implementation Method 1

The ultrafiltration pump is capable of performing ultrafiltration by drawing the dialysate in the dialysate introduction line through the ultrafiltration line

Methodology Applied
Scientific EffectPressure difference: Pressure Gradient

Implementation Method 2

a blood purification apparatus for performing purification treatment and ultrafiltration while causing blood of a patient to extracorporeally circulate

Methodology Applied
Scientific EffectDialysis: Diffusion

Data Source

PatentUS11931498B2Blood purification apparatus
Publication Date: 2024.03.19 NIKKISO CO LTD
  • US11931498B2 patent drawing
  • US11931498B2 patent drawing
  • US11931498B2 patent drawing

AI summary

A blood purification apparatus is provided in which waste liquid is prevented from flowing through an ultrafiltration pump during ultrafiltration so that the performance and accuracy of ultrafiltration can be maintained over a long period. The blood purification apparatus includes an ultrafiltration line one end of which is connected to a dialysate introduction line at a position on a downstream side with respect to a duplex pump. The ultrafiltration line is provided with the ultrafiltration pump. The ultrafiltration pump is capable of performing ultrafiltration by drawing dialysate in the dialysate introduction line through the ultrafiltration line such that the volume of the dialysate to be introduced into a dialyzer becomes smaller than the volume of waste liquid to be drained from the dialyzer.