Ultrasonic Ablation Probe with Real-Time Tissue Composition Analysis
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Solution Overview
Problem
Conventional techniques for analyzing the composition of biological tissue during ablation procedures require removing the tissue from the patient and performing analysis outside the system, leading to time-consuming delays and inefficient therapy.
Innovation Solution
A composition detector system is integrated within the ablation system, comprising a probe, an illumination source, and a spectrometer, which allows for in situ analysis of tissue composition by conveying mechanical or ultrasonic energy, illuminating the tissue, and receiving response illumination to provide real-time composition estimates.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If tissue is removed from the patient for composition analysis, then analysis can be performed, but time-consuming delays occur and therapy efficiency decreases
Solution Approach 1:
The patent combines the composition analysis system with the ablation system by integrating the spectrometer and illumination source directly into the ablation probe. This merging allows tissue to be analyzed in situ at the treatment site without removal, eliminating transport time and enabling real-time composition feedback during the ablation procedure.
Solution Approach 2:
The patent uses an optical fiber as an intermediary to transmit light from the illumination source to the tissue and to convey the reflected light signals back to the spectrometer. This intermediary enables remote analysis of tissue composition at the distal end of the probe without requiring physical removal of the tissue sample.
2Measurement precision
If conventional external analysis system is used, then composition analysis is possible, but the system complexity increases and procedural efficiency decreases
Solution Approach 1:
The patent integrates the illumination source, optical fibers, and spectrometer into a single unified ablation probe assembly. This consolidation reduces the number of separate components and interfaces required, simplifying the overall system architecture while enabling real-time composition analysis during the procedure.
Solution Approach 2:
The ablation probe is designed to perform multiple functions: delivering ultrasonic ablation energy, providing optical illumination, and collecting reflected light for spectral analysis. This multi-functionality eliminates the need for separate analysis equipment and reduces system complexity by having one device accomplish multiple tasks.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
Enables real-time adjustment of ablation therapy based on tissue composition, enhancing procedural efficiency and effectiveness by reducing delays and improving treatment accuracy.
Implementation Method 1
the probe can convey mechanical, acoustical, or ultrasonic energy to tissue of a patient to ablate the tissue
Implementation Method 2
The illumination can generate response illumination can be received by the spectrometer
Implementation Method 3
The spectrometer can analyze the response illumination and provide an estimate of the composition of the portion of tissue
Data Source
AI summary
A composition of a biological sample, such as tissue of a patient, can be estimated during an ablation procedure. A composition detector system can include a probe, an illumination source, and a spectrometer. A distal end of a probe can convey mechanical, acoustical, or ultrasonic energy to the tissue to ablate the tissue. The probe can extend through a working channel of a viewing scope. An illumination source can illuminate a portion of the tissue at the distal end of the probe or as the portion is being evacuated and collected for disposal. The illumination can generate response illumination from the portion of the tissue. The spectrometer can receive the response illumination, analyze the response illumination, and provide an estimate of the composition of the portion of tissue.