Ultrasonic Dispersion of Solid Medications

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Solution Overview

Problem

Conventional methods for dispersing solid medications into liquid form are inefficient, labor-intensive, and prone to inconsistencies, posing challenges for administration, especially in cases where manual crushing is difficult or impractical, leading to issues like gag reflex, aspiration, and inconsistent dosages.

Innovation Solution

An ultrasonic dispersion system and method that uses ultrasonic energy to efficiently convert solid medications into a liquid form, capable of processing various types of tablets and capsules quickly and consistently, minimizing contamination and user effort, and suitable for both automated and handheld use.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If manual crushing methods (mortar and pestle) are used to disperse solid medications, then the medication can be converted to liquid form, but the process is labor-intensive, time-consuming, and produces inconsistent particle sizes

Engineering Contradiction:
Improvedispersion speedVSAvoidcrushing time
Core Design Contradiction:
ProductivityVSLoss of time

Solution Approach 1:

The patent replaces manual mechanical crushing (mortar and pestle) with an ultrasonic dispersion system that uses high-frequency sound waves to break down solid medications. The ultrasonic probe generates cavitation bubbles in the liquid medium, which collapse and create micro-jets that fragment the solid particles, eliminating the need for manual labor and significantly reducing processing time while ensuring consistent particle size distribution.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

2Manufacturing precision

If manual crushing is performed to achieve complete dispersion, then solid particles are broken down, but the process requires considerable force and skill, leading to operator fatigue and inconsistent results

Engineering Contradiction:
Improveparticle size consistencyVSAvoidoperator skill requirement
Core Design Contradiction:
Manufacturing precisionVSEase of operation

Solution Approach 1:

The ultrasonic dispersion system replaces operator-dependent manual crushing with an automated ultrasonic field that consistently applies energy to break down particles. The system controls dispersion parameters (power, duration, amplitude) to achieve uniform particle size without requiring operator skill or physical effort, eliminating variability introduced by human factors.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The ultrasonic probe generates high-frequency mechanical vibrations (typically 20-100 kHz) that propagate through the liquid medium, creating cavitation and micro-streaming effects. These vibrations continuously act on the solid particles, breaking them down into uniform sizes without requiring manual intervention, thereby ensuring consistent particle size distribution independent of operator skill.

Inventive Principle:
Principle #18Mechanical vibration

3Reliability

If solid medications are crushed manually, then they can be administered to patients, but the process risks cross-contamination between different drugs and dosages

Engineering Contradiction:
Improvedosage accuracyVSAvoidcross-contamination risk
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The ultrasonic dispersion system performs drug dispersion in separate, dedicated containers for each medication, extracting the dispersion process from shared manual tools. Each drug is processed in its own beaker or vessel using the ultrasonic probe, eliminating the cross-contamination risk inherent in using a single mortar and pestle for multiple drugs. The system maintains dosage accuracy through controlled dispersion parameters while preventing contamination between different medications.

Inventive Principle:
Principle #2Taking out (Extraction)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The ultrasonic dispersion system enables rapid and reliable conversion of solid medications into liquid form, ensuring consistent dosages and reducing the risk of contamination and manual labor, while being adaptable for different medication types and forms.

Implementation Method 1

an ultrasonic transducer configured and operative to convert electrical energy to mechanical vibrations at ultrasonic frequencies

Methodology Applied
Scientific EffectUltrasonic vibration: Ultrasonic Vibration

Implementation Method 2

mechanical vibrations at ultrasonic frequencies sufficient to disperse the solid medications into the liquid form

Methodology Applied
Scientific EffectUltrasonic cavitation: Cavitation

Data Source

PatentUS9174176B2Ultrasonic dispersion apparatus, system, and method
Publication Date: 2015.11.03 DISPERSE SYST
  • US9174176B2 patent drawing
  • US9174176B2 patent drawing
  • US9174176B2 patent drawing

AI summary

An apparatus, system, and method of dispersing solid forms of drugs or medications reliably and consistently may generally employ ultrasonic energy. The disclosed embodiments facilitate preparation of a liquid dose from solid medications for administration to a patient.