2D Ultrasound Cross-Referencing Using Transformation Matrix Alignment

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Solution Overview

Problem

Conventional 2D ultrasound imaging relies on manual manipulation to capture 3D anatomy, leading to inefficient and inconsistent registration of orthogonal views, which is time-consuming and places high cognitive load on radiologists, resulting in variability and incorrect diagnoses.

Innovation Solution

A method and system for cross-referencing 2D ultrasound scans by generating orthogonal views and using correspondence transformation matrices to align pixel positions, enabling automated registration of 2D ultrasound images.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If two orthogonal sweeps of 2D ultrasound images are taken to capture 3D anatomy, then imaging resolution is improved, but the time required for mental cross-referencing and registration increases

Engineering Contradiction:
Improveimaging resolutionVSAvoidtime for mental cross-referencing
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The system creates a synthetic 2D representation of the target anatomy from the first sweep by projecting 3D volumetric data generated from the second sweep. This synthetic copy allows automatic alignment and cross-referencing between the two orthogonal views without requiring manual mental registration, thus resolving the time loss while maintaining high imaging resolution

Inventive Principle:
Principle #26Copying

Solution Approach 2:

The patent replaces the mechanical/mental process of manual image registration with an automated computational system. The system automatically determines correspondence transformation matrices and aligns pixel positions across different views using image processing algorithms, eliminating the time-consuming manual cross-referencing process

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

2Ease of operation

If freehand ultrasound sweeping is used to obtain 2D images, then ease of operation is improved, but image registration and matching becomes challenging

Engineering Contradiction:
Improveease of obtaining 2D imagesVSAvoiddifficulty of image registration
Core Design Contradiction:
Ease of operationVSDifficulty of detecting and measuring

Solution Approach 1:

The system introduces a synthetic 2D representation as an intermediary between the two orthogonal sweeps. This synthetic representation serves as a common reference framework that automatically aligns the first and second sweeps, resolving the registration difficulty while preserving the ease of freehand operation

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent transforms the problem by changing the parameter space from direct pixel-by-pixel registration to transformation matrix-based alignment. By determining correspondence transformation matrices that map pixel positions between views, the system simplifies the registration process while maintaining the flexibility of freehand sweeping

Inventive Principle:
Principle #35Parameter changes

3Reliability

If mental cross-referencing is performed by radiologists, then diagnostic accuracy is maintained, but cognitive load and variability increase

Engineering Contradiction:
Improvediagnostic accuracyVSAvoidcognitive load
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The system performs self-service by automatically generating the synthetic 2D representation and determining the correspondence transformation matrices without requiring radiologist intervention. This automation maintains diagnostic accuracy through consistent algorithmic processing while eliminating the cognitive load and variability associated with manual cross-referencing

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The patent substitutes the human cognitive process of mental cross-referencing with an automated computational system. The system automatically aligns images, determines correspondence relationships, and provides diagnostic support, thereby reducing cognitive load while maintaining reliable diagnostic accuracy through consistent, repeatable processing

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Data Source

PatentUS12611180B2Method and system for cross-referencing of two-dimensional (2D) ultrasound scans of a tissue volume
Publication Date: 2026.04.28 EXO IMAGING INC
  • US12611180B2 patent drawing
  • US12611180B2 patent drawing
  • US12611180B2 patent drawing

AI summary

A method for cross-referencing of 2D ultrasound scans of a tissue volume comprises generating first and second 2D representations of a target anatomy, respectively, from first and second series of 2D ultrasound images of the tissue volume generated. The method includes generating first and second simulated 2D representations of the target anatomy, respectively, from the second and first series of 2D ultrasound images. The 2D and simulated 2D representations are processed to at least substantially match pixel positions in the 2D and simulated 2D representations associated with the target anatomy. The method includes determining first and second correspondence transformation matrices from the processed 2D and simulated 2D representations, and using the first and second correspondence transformation matrices to determine, for a location in the second series of 2D ultrasound images associated with the target anatomy, a corresponding location in the first series of 2D ultrasound images.