Multiwell Underdrain Stand-off Ribs for Air Lock Prevention
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Solution Overview
Problem
Multiwell filtration devices, such as the Multiscreen® filter plate, face issues with leakage and incompatibility with automated robotics due to non-uniform dimensions and the tendency of the underdrain to disengage from wells, leading to contamination and air lock problems during filtration.
Innovation Solution
A redesigned underdrain system with improved structural integrity and venting capabilities, compliant with SBS guidelines, featuring a porous member for each well, stand-off ribs for spacing, and a collection plate configuration that allows for gas venting and secure fluid collection, ensuring consistent performance and compatibility with automated systems.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Ease of operation
If the underdrain is made removable for access to the membrane, then ease of operation is improved, but reliability deteriorates due to disengagement and leakage
Solution Approach 1:
The underdrain is divided into modular sections with individual well access, allowing selective removal of specific underdrain portions without disengaging the entire underdrain assembly. This segmentation maintains reliability while providing operational access.
Solution Approach 2:
The underdrain features nested structures where smaller components are housed within larger ones, allowing access to membrane through nested access points without compromising the overall sealed connection between underdrain and plate.
2Manufacturing precision
If the underdrain spout controls droplet size, then manufacturing precision is improved, but device complexity increases
Solution Approach 1:
The underdrain incorporates localized droplet control features only at specific spout locations where droplet size control is needed, rather than throughout the entire underdrain structure. This maintains manufacturing precision while minimizing added complexity.
Solution Approach 2:
Instead of using complex internal structures to control droplet size, the invention uses simplified external spout geometries where the droplet control function is achieved through the inverted or reversed design of the spout opening, reducing overall device complexity.
3Ease of operation
If the underdrain sits flat against the support surface, then ease of operation is improved, but reliability worsens due to local disengagement under vacuum
Solution Approach 1:
The underdrain incorporates excessive action by providing multiple discrete contact points and support ribs that ensure sufficient contact area with the support surface, preventing local disengagement even when the entire underdrain cannot sit perfectly flat.
Solution Approach 2:
The underdrain design changes the physical parameters of contact by incorporating raised ribs and adjusted thickness variations, transforming the contact interface from a continuous flat surface to discrete elevated contact points that maintain reliable sealing under vacuum conditions.
4Adaptability or versatility
If the plate conforms to SBS guidelines for automation, then adaptability is improved, but manufacturing precision requirements increase
Solution Approach 1:
The plate design incorporates universal features that satisfy multiple functions simultaneously: the dimensional specifications serve both as structural requirements and as automation compatibility interfaces, reducing the need for separate precision features.
Solution Approach 2:
The SBS guideline dimensional specifications are built into the plate design from the outset, with preliminary consideration of automation requirements embedded in the manufacturing tolerances and feature locations, eliminating the need for post-manufacturing adjustments.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The new underdrain design minimizes air lock, prevents leakage, and enhances structural integrity, ensuring reliable filtration and compatibility with automated laboratory instruments while maintaining compliance with SBS dimensional standards.
Implementation Method 1
a porous member for each well... which then directs fluid draining therefrom
Implementation Method 2
vents are defined which vent gases from the wells out of the device upon application of vacuum
Implementation Method 3
a plurality of stand-off ribs associated with each respective well are provided to provide spacing between the underdrain and the collection plate
Data Source
AI summary
Underdrain design for a multiwell device that when fixed to the device (either as an integral or removable component thereof), allows for adequate venting during filtration, minimizes or prevents air lock, and has improved structural integrity. Also disclosed is a laboratory device designed particularly for a multiplate format that includes a plate or tray having a plurality of wells, and an underdrain in fluid communication with each of the plurality of wells. The underdrain can be a separate, removable piece, or can be an integral unitary structure with the plate or tray forming a one-piece design. The design is preferably in compliance with SBS format.