Uniform Coating Layer for Hybrid Substrate Surface Masking

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Solution Overview

Problem

In analytical operations, hybrid surfaces with different material regions having distinct properties complicate chemical and biochemical analyses due to differential interactions with analytical samples, leading to adverse effects such as adsorption, corrosion, and signal noise.

Innovation Solution

A uniform masking or coating layer is applied over hybrid substrate surfaces comprising different material regions, providing a uniform surface with consistent chemical or physical properties to minimize adverse interactions and optimize reaction conditions.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Adaptability or versatility

If a hybrid substrate with different material regions is used, then the substrate provides diverse functional properties, but the differential interactions with analytical samples cause adsorption, corrosion, and signal noise

Engineering Contradiction:
Improvefunctional propertiesVSAvoidadsorption, corrosion, signal noise
Core Design Contradiction:
Adaptability or versatilityVSObject-affected harmful factors

Solution Approach 1:

A uniform masking layer is applied over the hybrid substrate surface to act as an intermediary between the diverse material regions and the analytical sample. This single-layer approach provides a consistent surface property that mediates interactions, preventing direct contact between the sample and the heterogeneous underlying materials, thereby eliminating differential interactions while preserving the functional diversity of the substrate.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Reliability

If multiple coating layers are applied to mask different material regions, then uniform surface properties are achieved, but the device complexity increases

Engineering Contradiction:
Improveuniform surface propertiesVSAvoidnumber of coating layers
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

Multiple coating functions are merged into a single masking layer that uniformly covers the entire hybrid substrate surface. Instead of applying separate coatings to different material regions, the invention uses one comprehensive masking layer that simultaneously masks all underlying material regions, achieving uniform surface properties while minimizing structural complexity.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The masking layer is designed to perform multiple functions simultaneously: it provides a uniform surface for consistent sample interactions, masks all underlying material regions regardless of their diversity, and can be applied as a single universal layer across the entire substrate. This multi-functional approach eliminates the need for region-specific coatings.

Inventive Principle:
Principle #6Universality (Multi-functionality)

3Object-affected harmful factors

If a uniform masking layer is applied over hybrid substrate, then non-specific interactions are reduced, but the manufacturing precision requirements increase

Engineering Contradiction:
Improvenon-specific interactionsVSAvoidcoating uniformity
Core Design Contradiction:
Object-affected harmful factorsVSManufacturing precision

Solution Approach 1:

The invention changes the approach from region-specific variable coatings to a single uniform masking layer with consistent parameters across the entire substrate. By applying one coating with uniform thickness and composition over all material regions, the method reduces non-specific interactions while managing manufacturing precision through standardized coating parameters rather than variable region-specific parameters.

Inventive Principle:
Principle #35Parameter changes

Data Source

PatentUS7935310B2Uniform surfaces for hybrid material substrate and methods for making and using same
Publication Date: 2011.05.03 PACIFIC BIOSCIENCES OF CALIFORNIA INC
  • US7935310B2 patent drawing
  • US7935310B2 patent drawing
  • US7935310B2 patent drawing

AI summary

Devices, systems and methods of using same where hybrid substrate materials are provided with a substantially uniform surface to provide uniformity of properties, including interaction with their environments. Uniform surfaces are applied as coatings over, e.g., hybrid metal/silica, metal/polymer, metal/metal surfaces to mask different chemical properties of differing regions of the surface and to afford a protective surface for the hybrid structure.