Unsupervised Deep Learning Diagnostic System for Medical Image Analysis

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Solution Overview

Problem

Current medical imaging analysis methods require extensive manual annotation and do not effectively utilize larger visual contexts, making them inefficient for identifying anatomical features in medical images, such as spinal column tumors.

Innovation Solution

A computer-assisted diagnostic system employing unsupervised deep learning for encoding medical image patterns, using a neural autoencoder to reduce data encodings, and a comparison module to match these patterns with reference images, allowing for automated identification and semantic description of anatomical structures without manual feature specification.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If machine classifiers with manually annotated training sets are used, then identification accuracy of lesions is improved, but the complexity of training data preparation and time consumption increase significantly

Engineering Contradiction:
Improveidentification accuracyVSAvoidtraining data preparation complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The system performs self-training by automatically generating pseudo-labels for unannotated images through iterative refinement. The classifier continuously improves its own performance by identifying lesions in unannotated data and using these predictions to expand its training set, eliminating the need for extensive manual annotation while maintaining high accuracy.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The system performs preliminary identification of lesions in unannotated images to create initial training data. By pre-processing unannotated images and generating preliminary lesion masks, the system prepares training data automatically before formal model training, reducing the burden of manual annotation while ensuring sufficient training material is available.

Inventive Principle:
Principle #10Preliminary action

2Measurement precision

If machine classifiers with manually annotated training sets are used, then identification accuracy of lesions is improved, but the time required for diagnosis increases

Engineering Contradiction:
Improveidentification accuracyVSAvoiddiagnosis time
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The system automatically expands its own training set by identifying lesions in unannotated images and using these predictions for self-supervised learning. This self-service mechanism eliminates the time-consuming manual annotation process while maintaining high identification accuracy, thereby reducing overall diagnosis time without sacrificing precision.

Inventive Principle:
Principle #25Self-service

3Measurement precision

If image analysis methods focus on local lesion features, then lesion detection precision is improved, but the loss of visual context information increases

Engineering Contradiction:
Improvelesion detection precisionVSAvoidvisual context information
Core Design Contradiction:
Measurement precisionVSLoss of information

Solution Approach 1:

The system employs a nested architecture where a local lesion detector is embedded within a broader anatomical context analyzer. The local detector identifies precise lesion boundaries while the outer context module analyzes surrounding anatomical structures and their relationships, ensuring both high detection precision and preservation of visual context information about the entire organ or body region.

Inventive Principle:
Principle #7Nested doll (Nesting)

Data Source

PatentUS10176580B2Diagnostic system and diagnostic method
Publication Date: 2019.01.08 SIEMENS HEALTHINEERS AG
  • US10176580B2 patent drawing
  • US10176580B2 patent drawing

AI summary

A first interface for reading a medical patient image record is provided. Furthermore, provision is made of an encoding module for machine-based learning of data encodings of image patterns by an unsupervised deep learning and for establishing a deep-learning-reduced data encoding of a patient image pattern contained in the patient image record. Furthermore, provision is made of a comparison module for comparing the established data encoding with reference encodings of reference image patterns stored in a database and for selecting a reference image pattern with a reference encoding which is similar to the established data encoding. An assignment module serves to establish a key term assigned to the selected reference image pattern and to assign the established key term to the patient image pattern. A second interface is provided for outputting the established key term with assignment to the patient image pattern.