Uracil Crystal Purification via Solvent Precipitation
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Solution Overview
Problem
Existing methods for producing uracil compounds on an industrial scale struggle to achieve high purity, which is crucial for effective herbicide performance.
Innovation Solution
A method involving the dissolution of a crude uracil composition in a mixture of C3-C6 alcohol solvents and aromatic solvents, followed by precipitation to obtain high-purity crystals of the uracil compound.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Manufacturing precision
If conventional multistep reaction process is used for industrial-scale production, then production capability is achieved, but product purity is insufficient
Solution Approach 1:
The patent extracts and removes impurity components from the reaction mixture through selective crystallization. By controlling temperature and solvent conditions, the target uracil compound crystallizes in a pure form while impurities remain in the mother liquor, achieving high purity (99.5% or higher) while maintaining industrial-scale production capability
Solution Approach 2:
The patent utilizes parameter changes in the crystallization process, specifically temperature variation and solvent composition adjustment, to control the crystallization of the uracil compound. By changing these parameters, the compound transitions from dissolved state to crystalline state with high purity, resolving the contradiction between production scale and purity
2Manufacturing precision
If purification methods are intensified to achieve high purity, then product purity improves, but process complexity increases
Solution Approach 1:
The patent performs preliminary action by optimizing the reaction conditions and selecting appropriate solvents before the crystallization step. This preliminary preparation ensures that impurities are minimized and the target compound is ready for efficient crystallization, achieving high purity without requiring complex subsequent purification steps
Solution Approach 2:
The patent uses a specific solvent system as an intermediary medium to facilitate the separation of the uracil compound from impurities. The solvent acts as a mediator that selectively dissolves the target compound at elevated temperatures and allows its pure crystallization upon cooling, simplifying the overall purification process
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
This method effectively produces uracil compound crystals with high purity, suitable for industrial-scale herbicide production, by utilizing specific solvent combinations and precipitation techniques.
Implementation Method 1
dissolving a crude uracil composition in organic solvents consisting of a C3-C6 alcohol solvent and an aromatic solvent to obtain a solution
Implementation Method 2
precipitating a crystal of the present uracil compound from the solution
Implementation Method 3
the crystal of the present uracil compound is precipitated by cooling a solution of a crude uracil composition
Data Source
AI summary
The invention provides a method for producing a crystal of a uracil compound with high purity by a process which can be carried out in an industrial scale. Specifically, the invention provides a method for producing a crystal of a uracil compound, wherein the method involves dissolving a composition containing a uracil compound represented by formula (1)in organic solvents consisting of a C3-C6 alcohol solvent and an aromatic solvent to obtain a solution, and precipitating a crystal of said uracil compound from the solution.