Urease-Mediated Urine Sample Measurement for Accuracy

The patent introduces urease as an intermediary substance that specifically targets and decomposes urea. The urease catalyzes the hydrolysis of urea into ammonia and carbon dioxide, effectively removing the interfering substance before the optical measurement occurs. This allows the use of simple optical equipment while achieving accurate measurements by eliminating the urea interference through the enzymatic intermediary.

The patent applies preliminary action by adding urease to the urine sample before performing the optical measurement. The urease is allowed to act on the urea in advance, decomposing it into non-interfering products. This preliminary decomposition ensures that when the subsequent optical measurement is performed, the interfering urea has already been removed, thereby improving measurement accuracy without requiring complex equipment.

Instead of using special components or complex measurement devices, the patent employs urease as a chemical intermediary that simplifies the measurement process. The urease selectively binds to and decomposes urea, converting it into ammonia and carbon dioxide. This intermediary approach allows standard optical equipment to achieve high measurement accuracy for trace materials by eliminating urea interference, thereby avoiding the need for complex specialized components.

The patent changes the chemical parameters of the sample by introducing urease, which alters the composition of the urine sample through enzymatic decomposition. This parameter change (converting urea to ammonia and CO2) improves the measurement accuracy of trace materials by modifying the sample's chemical environment, allowing simple optical devices to achieve results that would otherwise require complex specialized equipment.

The patent uses urease as an intermediary to resolve the conflict between preserving urine composition and ensuring measurement reliability. The urease selectively targets urea molecules, binding to them and catalyzing their decomposition into ammonia and carbon dioxide. This intermediary action removes the interfering urea while leaving other physiological components intact, thereby maintaining the representativeness of the urine sample while improving measurement reliability of antigen-antibody aggregates.

The patent converts the harmful effect of urea interference into a beneficial process by utilizing urease to decompose urea. The urea that originally caused measurement errors is transformed through enzymatic hydrolysis into ammonia and carbon dioxide, which do not interfere with the optical measurement. This conversion turns the problematic urea presence into an opportunity for selective removal, improving measurement reliability while preserving the physiological significance of the urine sample.