Uridine and Omega-3 PUFA Composition for Limb Motor Function

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Solution Overview

Problem

Current nutritional approaches do not specifically address the decline in limb functioning, particularly in coordination, balance, grip strength, and fine motor skills, which are often impaired due to neurological disorders or aging.

Innovation Solution

A combination of a uridine source and omega-3 polyunsaturated fatty acids with 18-24 carbon atoms, optionally with additional active ingredients like vitamin D and butyrate-producing fibers, is administered to improve limb functions by enhancing neurological functioning.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Adaptability or versatility

If general nutritional approaches are used to support brain function, then cognitive and emotional functions may be improved, but specific limb functions (coordination, balance, grip strength, fine motor skills) are not specifically addressed

Engineering Contradiction:
Improvespecificity for limb function improvementVSAvoidlack of specific component combination
Core Design Contradiction:
Adaptability or versatilityVSQuantity of substance

Solution Approach 1:

The patent applies local quality by transitioning from general brain function support to specific limb function improvement. The composition uses a targeted combination of uridine source and omega-3 PUFA specifically for enhancing coordination, balance, grip strength, and fine motor skills, rather than providing broad neurological support. This localized approach addresses the specific needs of limb functioning identified in the technical problem.

Inventive Principle:
Principle #3Local quality

Solution Approach 2:

The patent employs composite materials by creating a specific combination of uridine source and omega-3 polyunsaturated fatty acid (18-24 carbon atoms). This composite composition synergistically enhances limb functions that neither component alone could achieve. The combination represents a novel formulation specifically designed for improving coordination, balance, and motor skills, resolving the contradiction between general nutrition and specific limb function support.

Inventive Principle:
Principle #40Composite materials

2Reliability

If existing lipid fractions are used to support brain function, then energy provision and general neurological support are achieved, but coordination and balance specifically are not improved

Engineering Contradiction:
Improveeffectiveness for coordination and balanceVSAvoidcomposition formulation complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent applies parameter changes by specifying precise compositional parameters: uridine source combined with omega-3 PUFA having 18-24 carbon atoms. This specific parameter definition ensures the composition effectively improves coordination and balance. The formulation transitions from general lipid fractions to a precisely defined combination with specific molecular characteristics, enhancing reliability for neurological function improvement.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent uses an intermediary approach by identifying uridine source and omega-3 PUFA as key mediatory components that specifically enhance coordination and balance. These intermediaries act as the active agents bridging the gap between general nutritional intake and specific limb function improvement. The combination serves as a mediating formulation that translates general nutrition into targeted neurological benefits.

Inventive Principle:
Principle #24Intermediary (Mediator)

3Productivity

If uridine source and omega-3 PUFA combination is used, then coordination and balance are significantly improved, but the formulation complexity increases

Engineering Contradiction:
Improverate of limb function improvementVSAvoidcomposition formulation complexity
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The patent applies merging by combining uridine source and omega-3 PUFA into a single integrated composition. This unified formulation delivers synergistic effects that accelerate limb function improvement compared to separate interventions. The merged composition presents a cohesive solution that enhances coordination, balance, grip strength, and fine motor skills while managing formulation complexity through integrated delivery.

Inventive Principle:
Principle #5Merging (Combining)

Data Source

PatentEP3919053A1Composition comprising a uridine source, an omega-3 PUFA for improving coordination, balance, grip strength or fine motor skills
Publication Date: 2021.12.08 NV NUTRICIA
  • EP3919053A1 patent drawingFigure 1~2
  • EP3919053A1 patent drawing
  • EP3919053A1 patent drawing

AI summary

The invention is directed to a combination of a uridine source and an omega-3-polyunsaturated fatty acid having 18-24 carbon atoms for use in - the prevention or treatment of a disturbance in coordination of limbs in a mammal - the prevention or treatment of a disturbance in equilibrium in a mammal - for use in the prevention or treatment of a disturbance in limb strengthA combination of a uridine source and an omega-3-polyunsaturated fatty acid having 18-24 carbon atoms - or use in the prevention or treatment of a disturbance in a motor skill in a mammal.