Urine Analysis Device with Automated Sampling and Electrochemical Detection

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Solution Overview

Problem

Current urine analysis methods are lengthy, require continuous medical personnel presence, and are prone to contamination and sub-optimal results due to variable urine composition and temperature sensitivity, making them difficult to perform and interpret.

Innovation Solution

A urine analysis device that performs electrochemical analysis of pH, sodium, potassium, ammonium, and chloride contents without reagents, using a sampler module with automatic urine handling and temperature control, allowing for autonomous and frequent monitoring of urine flow and physico-chemical characteristics.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of operation

If manual urine collection and analysis procedures are used, then medical personnel can perform the analysis, but the procedure becomes lengthy and requires continuous presence of medical personnel

Engineering Contradiction:
Improveease of operationVSAvoidexamination time
Core Design Contradiction:
Ease of operationVSLoss of time

Solution Approach 1:

The device segments the urine analysis process into automated modular components: automatic urine collection from catheter, filtration, reagent mixing, and electrochemical analysis. This segmentation eliminates manual intervention steps while maintaining analysis quality, resolving the contradiction between ease of operation and time consumption.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The device enables self-service automated urine analysis by collecting urine directly from the catheter, automatically mixing reagents, and performing measurements without requiring medical personnel presence. The system serves itself through automated sampling, preparation, and analysis functions.

Inventive Principle:
Principle #25Self-service

2Reliability

If manual urine sampling is performed by operators, then the sample can be collected, but contamination risk increases

Engineering Contradiction:
Improvesample purityVSAvoidoperation simplicity
Core Design Contradiction:
ReliabilityVSEase of operation

Solution Approach 1:

The device extracts the urine sample directly from the catheter through an automated sampling system, eliminating the need for manual collection by operators. This extraction approach prevents contamination that would occur during manual handling, transfer, and storage steps.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The device introduces an automated sampling system as an intermediary between the catheter and analysis chamber, replacing manual operator intervention. This intermediary mechanism ensures sterile, contamination-free sample collection while maintaining operational simplicity.

Inventive Principle:
Principle #24Intermediary (Mediator)

3Measurement precision

If different dilution with reagents is applied for variable urine content, then analysis accuracy can be maintained, but the analysis becomes more complicated

Engineering Contradiction:
Improveanalysis accuracyVSAvoidanalysis complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The device dynamically adjusts reagent dilution ratios based on real-time detection of urine concentration parameters. This dynamic adaptation maintains measurement precision across varying urine compositions while the automated control system manages the complexity, preventing it from becoming a manual burden.

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The system incorporates feedback mechanisms that detect urine content variability and automatically adjust reagent mixing ratios accordingly. This closed-loop control maintains analysis accuracy while eliminating the need for manual calculation and adjustment of dilutions.

Inventive Principle:
Principle #23Feedback

4Productivity

If frequent urine analyses are performed, then patient monitoring is improved, but continuous medical personnel presence is required

Engineering Contradiction:
Improveanalysis frequencyVSAvoidoperational simplicity
Core Design Contradiction:
ProductivityVSEase of operation

Solution Approach 1:

The device enables continuous automated urine analysis by directly connecting to the catheter and performing measurements at scheduled intervals without requiring medical personnel presence between tests. This continuous operation capability increases analysis frequency while maintaining operational simplicity through automation.

Inventive Principle:
Principle #20Continuity of useful action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables simple, fast, and frequent urine analysis without medical personnel, providing accurate and consistent results by automating the sampling and analysis process, reducing contamination risks and improving analysis efficiency.

Implementation Method 1

One of the main types of analysis is electrochemical analysis in which the potential difference between a pair of electrodes is calculated and, based on this, the pH, sodium, potassium, ammonium and chloride content within the urine is determined.

Methodology Applied
Scientific EffectElectrochemical analysis:

Implementation Method 2

The device (1) comprises at least a first sampler module (2), which is part of an inlet system for placing a fluid to be analysed inside the device (1). In particular, the first sampler module (2) is configured to be placed in fluid passage connection with a user.

Methodology Applied
Scientific EffectTemperature control:

Data Source

PatentEP4147640A1Urine analysis device
Publication Date: 2023.03.15 KURES SRL
  • EP4147640A1 patent drawingFigure 1
  • EP4147640A1 patent drawingFigure 2~3
  • EP4147640A1 patent drawingFigure 4a~4b

AI summary

It is provided a urinalysis device (1) capable of analysing a urine sample to determine the value of physico-chemical characteristics of the urine sample and comprising a first sampler module (2) configured to be placed in fluid passage connection with a user and comprising a first drain drainage duct (20) comprising a containment part (20a) defining a predetermined volume and configured to hold a first portion of urine, and a release part (20b) configured to convey a second portion of urine out of the first sampler module (2); a diuresis bag (3) in fluid passage connection with at least the release part (20b) and configured to collect the second portion of urine; an analysis apparatus (4) placed in fluid passage connection with the containment part (20a) and configured to analyse at least part of the first urine portion; control means (5) operatively connected to the analysis apparatus (4) and configured at least to process data collected by the analysis apparatus (4); and a second sampler module (7) operatively connected to the analysis apparatus (4) and including an shut-off valve (70) in fluid passage connection with the analysis apparatus (4) and configured to accommodate a syringe engagement including sampled urine so that the analysis apparatus (4) can analyse the sampled urine.