Urine Organic Acid Analysis for Health Assessment

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Solution Overview

Problem

Current methods lack comprehensive and accurate health assessment tools to detect early signs of health changes or disease development in individuals, relying on gradual and continuous monitoring of bodily functions to prevent disease progression.

Innovation Solution

A method utilizing liquid chromatography tandem mass spectrometry to analyze organic acids in urine, categorizing them into indicators for fatty acid, carbohydrate, mitochondrial energy, vitamin B complex, oxidative damage, and intestinal digestion, providing ideal and reference values to evaluate health status and recommend personalized health promotions.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If comprehensive health assessment is needed to detect early signs of health changes, then measurement precision is improved, but device complexity increases

Engineering Contradiction:
Improvehealth assessment precisionVSAvoidtesting system complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent segments the complex health assessment into four distinct indicator categories (fatty acid metabolism, carbohydrate metabolism, mitochondrial energy generation, and intestinal digestion function), each measured through specific organic acid markers in urine. This segmentation allows comprehensive health evaluation while organizing the complexity into manageable, interpretable components

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent uses urine organic acids as intermediary substances that reflect internal metabolic processes. By measuring these external urinary markers, the system indirectly assesses complex internal health status without requiring direct measurement of metabolic processes, thus reducing system complexity while maintaining measurement precision

Inventive Principle:
Principle #24Intermediary (Mediator)

2Loss of information

If multiple organic acid indicators are measured to assess various metabolic functions, then information completeness is improved, but loss of time increases

Engineering Contradiction:
Improvehealth information completenessVSAvoidtesting time
Core Design Contradiction:
Loss of informationVSLoss of time

Solution Approach 1:

The patent combines multiple organic acid measurements into a single integrated urine test that simultaneously evaluates fatty acid metabolism, carbohydrate metabolism, mitochondrial energy generation, and intestinal digestion function. This merging approach provides comprehensive health information in one test rather than requiring multiple separate tests, thus reducing time loss while maintaining information completeness

Inventive Principle:
Principle #5Merging (Combining)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables precise health status evaluation by identifying deviations in organic acid levels, allowing for timely interventions and personalized health recommendations to maintain or improve health, thereby preventing disease progression.

Implementation Method 1

using a liquid chromatography tandem mass spectrometry to analyze the urine specimens

Methodology Applied
Scientific EffectChromatography: Chromatography

Implementation Method 2

using a liquid chromatography tandem mass spectrometry to analyze the urine specimens to obtain multiple values of organic acids

Methodology Applied
Scientific EffectMass spectrometry:

Data Source

PatentUS20250012780A1Application of Organic Acids in Urine for Health Management
Publication Date: 2025.01.09 OU YUNG-CHUN
  • US20250012780A1 patent drawing

AI summary

The present invention provides an application of organic acids in urine for health management, used for testing urine specimens of the human body by using a liquid chromatography tandem mass spectrometry to analyze the urine specimens to obtain multiple values of organic acids in the urine. The test values include ideal values and reference values; when the values are within the ideal value range, the health status is assessed as healthy; when the values are within the reference value range, the health status is assessed as sub-healthy; when the values are outside the ideal and reference value ranges, the health status is assessed as having a risk of developing diseases. Therefore, the application of organic acids in urine for health management according to the present invention enables the development of various health management and anti-aging plans, as well as prevention and treatment of chronic diseases.