UV-C Liquid Nitrogen Sterilization Before Cryogenic Evaporation

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Solution Overview

Problem

Existing methods fail to guarantee the sterility of liquid nitrogen during transportation and handling due to its rapid evaporation and contamination risks, particularly in medical and culinary applications where direct sterilization in the liquid state is necessary.

Innovation Solution

A device and method utilizing UV-C radiation with a controlled germicidal lamp system, thermally insulated and programmed for efficient sterilization within commercially available containers, ensuring effective sterilization before liquid nitrogen evaporates.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of operation

If liquid nitrogen is transported in pressurized containers through multiple hands, then it can be delivered to end users, but contamination risks increase during transfers

Engineering Contradiction:
Improvetransportation to end userVSAvoidsterility guarantee
Core Design Contradiction:
Ease of operationVSReliability

Solution Approach 1:

The system performs preliminary sterilization of liquid nitrogen using UV-C radiation before the nitrogen is used for cryopreservation. The sterilization unit is positioned to irradiate the liquid nitrogen in the storage container, eliminating microorganisms and ensuring sterility is established in advance, preventing contamination during subsequent handling and transfers.

Inventive Principle:
Principle #10Preliminary action

2Reliability

If conventional sterilization methods are used on liquid nitrogen, then sterility can be achieved, but the rapid evaporation of liquid nitrogen makes these methods difficult to apply

Engineering Contradiction:
Improvesterility assuranceVSAvoidapplicability to evaporating liquids
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The invention replaces mechanical sterilization methods (heating, filtration) with UV-C radiation sterilization. The UV-C sterilization unit emits ultraviolet radiation that penetrates the liquid nitrogen without being affected by its low temperature or rapid evaporation, providing effective sterilization adapted to the specific properties of cryogenic liquids.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

3Reliability

If liquid nitrogen is sterilized in gaseous state through ultrafiltration and UV irradiation, then purification can be achieved, but the process becomes complex and requires evaporation and recompression

Engineering Contradiction:
Improvepurification effectivenessVSAvoidprocess steps
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The invention extracts and eliminates the unnecessary steps of evaporation, ultrafiltration, and recompression from the sterilization process. By applying UV-C radiation directly to liquid nitrogen in its liquid state, the system achieves sterilization through a single, simplified operation, removing the complex multi-step process while maintaining purification effectiveness.

Inventive Principle:
Principle #2Taking out (Extraction)

4Reliability

If sterilization is performed rapidly before evaporation, then sterility can be guaranteed, but the sterilization time must be precisely controlled

Engineering Contradiction:
Improvesterility before evaporationVSAvoidsterilization time control
Core Design Contradiction:
ReliabilityVSLoss of time

Solution Approach 1:

The system incorporates a timer that controls the duration of UV-C radiation exposure. The timer ensures the liquid nitrogen is irradiated for the precise time needed to achieve sterilization before significant evaporation occurs, providing time-based feedback control to optimize the balance between sterilization effectiveness and nitrogen retention.

Inventive Principle:
Principle #23Feedback

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The solution provides rapid and direct sterilization of liquid nitrogen in its liquid state, ensuring high sterility assurance for cryopreservation, cryotherapy, and molecular gastronomy applications, preventing microbial contamination and ensuring safe use.

Implementation Method 1

subjecting the liquid nitrogen to a UV-C radiation dose sufficient to destroy any micro-organisms and viruses present

Methodology Applied
Scientific EffectUltraviolet radiation: Radiation

Data Source

PatentUS20120102983A1Device and method for sterilizing liquid nitrogen by ultraviolet radiation
Publication Date: 2012.05.03 NTERILIZER SRL
  • US20120102983A1 patent drawing
  • US20120102983A1 patent drawing
  • US20120102983A1 patent drawing

AI summary

Described are a device and a method for rapidly sterilizing liquid nitrogen in a container using ultraviolet radiation irradiated for a predetermined length of time based on the temperature measured by a sensor and on the minimum dose of radiation necessary to kill micro-organisms resistant to liquid nitrogen.