Vacuum Carrier for Biomolecule Chip Fixation

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Solution Overview

Problem

Conventional gene sequencers damage chips due to direct pressure application, which can lead to breakage during the sequencing process.

Innovation Solution

A carrier apparatus with a vacuum system that generates a negative pressure of at least −60 kPa to adsorb and fix the chip to a carrier surface, preventing damage and ensuring accurate sequencing.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If pressure devices are used to fix the chip, then the chip is secured to the workbench, but the chip exterior is damaged or the chip breaks

Engineering Contradiction:

Improvechip fixation reliabilityVSAvoidchip damage from pressure

Core Design Contradiction:

ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent replaces the mechanical pressure-based fixation system with a vacuum-based fixation system. Instead of using pressure plates or elastic clamp plates that directly contact and press on the chip exterior, the invention uses a vacuum environment to create negative pressure that adsorbs the chip to the carrier surface through atmospheric pressure differential, thereby eliminating direct mechanical contact and pressure-induced damage

Inventive Principle:

Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent applies pneumatic principles by using vacuum (negative pressure) to fix the chip. The vacuum system creates a pressure differential between the interior of the chip carrier and the exterior atmosphere, causing atmospheric pressure to press the chip against the carrier surface without requiring direct mechanical contact from pressure devices

Inventive Principle:

Principle #29Pneumatics and hydraulics

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The vacuum-based fixation method effectively secures the chip without causing damage, ensuring the accuracy of subsequent sequencing processes and reducing the risk of chip breakage.

Implementation Method 1

a vacuum system that communicates with the space to be vacuumized and causes a negative pressure of greater than or equal to −60 kPa to be generated in the space to be vacuumized, thereby causing the chip to be adsorbed and fixed to the carrier surface

Methodology Applied

Scientific EffectNegative pressure adsorption: Adsorption

Data Source

PatentUS20250099956A1Carrier apparatus and biomolecule detection system

Publication Date: 2025.03.27 GENEMIND BIOSCIENCES CO LTD

AI summary

The present disclosure relates to the technical field of biomolecule detection systems and to a carrier apparatus and a biomolecule detection system. The carrier apparatus includes: a carrier structure that includes a carrier stage provided with a carrier surface configured to carry a chip, the carrier stage including a space to be vacuumized therein; and a vacuum system that communicates with the space to be vacuumized and causes a negative pressure of greater than or equal to −60 kPa to be generated in the space to be vacuumized, thereby causing the chip to be adsorbed and fixed to the carrier surface. In the carrier apparatus of the embodiments, arranging the carrier structure provided with the carrier stage including the space to be vacuumized therein in fit with the vacuum system enables the negative pressure to be generated in the space to be vacuumized to adsorption-fix the chip.