Vaginal Microbiota Composition for Restoring Lactobacillus Balance
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Solution Overview
Problem
Current treatments for vaginal health conditions such as bacterial vaginosis, candidiasis, and gynecological cancers lack effective alternatives that restore the normal balance of vaginal microbiota, leading to inadequate solutions for maintaining reproductive health.
Innovation Solution
A vaginal microbiota composition comprising a mixture of Lactobacillus species like Lactobacillus crispatus, Lactobacillus iners, Lactobacillus gasseri, and others, administered via suppositories or capsules, aimed at normalizing the vaginal microbiome to prevent infections and promote health.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If current treatments for vaginal health conditions are used, then infections may be temporarily suppressed, but the normal balance of vaginal microbiota is not restored
Solution Approach 1:
The patent extracts and isolates specific beneficial Lactobacillus species from the vaginal microbiota, purifying them for therapeutic use. This allows the beneficial bacteria to be separated from the diseased environment and reintroduced in a controlled manner to restore microbiota balance without the harmful components that caused the infection
Solution Approach 2:
The patent discards harmful pathogens and imbalanced microbial compositions, then recovers and reintroduces the beneficial Lactobacillus species. This process eliminates the harmful elements while preserving and restoring the beneficial components of the vaginal microbiota
2Ease of operation
If a single Lactobacillus species is used for treatment, then the treatment is simple and easy to administer, but it may not effectively restore the diverse normal vaginal microbiota
Solution Approach 1:
The patent combines multiple Lactobacillus species (L. crispatus, L. iners, L. gasseri, L. jensenii, and others) into a single composite therapeutic composition. This merging approach maintains the simplicity of administering one product while restoring the natural diversity of the vaginal microbiota through the synergistic action of multiple bacterial species
Solution Approach 2:
The patent creates a composite microbial preparation containing multiple Lactobacillus species in specific proportions. This composite composition mimics the natural complexity of healthy vaginal microbiota while maintaining the ease of single-dose administration, effectively bridging the gap between simplicity and biological complexity
Data Source
AI summary
Compositions and methods for treating patients are disclosed. An example composition may include a vaginal microbiota composition. The vaginal microbiota composition may include a mixture of bacteria. The mixture of bacteria may include Lactobacillus crispatus, Lactobacillus gasseri, Lactobacillus jensenii, and Lactobacillus rhamnosus.