Valerian Root and Lavender Oil Synergistic Sleep Treatment

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

Current medical agents for sleep disorders often have broad side effects such as addiction and tolerance development, and there is a need for more effective treatments with lower side effects, particularly in the form of natural compounds.

Innovation Solution

A combination of valerian root extract and lavender oil, prepared using aqueous ethanol or methanol extraction, is used for oral treatment of sleep disorders, potentially enhanced by simultaneous or sequential administration to achieve synergistic effects.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If current medical agents are used for treating sleep disorders, then sleep treatment effectiveness is achieved, but side effects such as addiction and tolerance development occur

Engineering Contradiction:
Improvesleep treatment effectivenessVSAvoidside effects including addiction and tolerance
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent combines valerian root extract and lavender oil in a synergistic formulation where the two natural compounds work together to enhance sleep-inducing effects. The combination produces an overadditive effect where the total effect exceeds the sum of individual effects, providing effective sleep treatment without the harmful side effects associated with conventional pharmaceutical agents.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The patent employs natural compounds (valerian root extract and lavender oil) that are biodegradable and do not accumulate in the body like synthetic pharmaceuticals. These natural substances are metabolized and eliminated without causing long-term adverse effects, addiction, or tolerance development, effectively replacing persistent harmful chemical agents with transient natural alternatives.

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

2Object-affected harmful factors

If natural compounds are used for sleep treatment, then side effects are reduced, but treatment effectiveness may be insufficient

Engineering Contradiction:
Improveside effect rateVSAvoidtreatment effectiveness
Core Design Contradiction:
Object-affected harmful factorsVSReliability

Solution Approach 1:

The patent merges valerian root extract and lavender oil in a synergistic formulation where the two natural compounds work together to enhance sleep-inducing effects. The combination produces an overadditive effect where the total effect exceeds the sum of individual effects, providing effective sleep treatment without the harmful side effects associated with conventional pharmaceutical agents.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The patent creates a composite natural formulation combining two different plant extracts (valerian root and lavender) that have complementary mechanisms of action. This composite approach leverages the synergistic interaction between the compounds to achieve pharmaceutical-level effectiveness while maintaining the safety profile of natural substances.

Inventive Principle:
Principle #40Composite materials

3Reliability

If valerian root extract is used alone for sleep disorders, then some sleep-inducing effect is achieved, but the effect is weak and insufficient

Engineering Contradiction:
Improvesleep-inducing effectVSAvoiddosage required for effective treatment
Core Design Contradiction:
ReliabilityVSQuantity of substance

Solution Approach 1:

The patent combines valerian root extract and lavender oil in a synergistic formulation where the two natural compounds work together to enhance sleep-inducing effects. The combination produces an overadditive effect where the total effect exceeds the sum of individual effects, providing effective sleep treatment without the harmful side effects associated with conventional pharmaceutical agents.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The patent changes the effective concentration parameter by combining two active compounds, where the synergistic interaction amplifies the biological effect per unit of active substance. This allows achieving therapeutic effects at lower total dosages compared to using valerian root extract alone, improving the efficiency of treatment.

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The combination of valerian root extract and lavender oil demonstrates a synergistic overadditive effect in improving sleep quality with low side effects, as shown in in vivo trials and verified in human patients, offering a potent natural treatment for sleep disorders.

Implementation Method 1

the valerian root extract is prepared by extraction with aqueous ethanol or aqueous methanol, wherein ethanol and water are used in a volume ratio of 30/70 to 90/10 or methanol and water are used in a volume ratio of 40/60 to 55/45 in the extraction

Methodology Applied
Scientific EffectExtraction: Liquid-Liquid Extraction

Data Source

PatentUS10357530B2Combination of valerian root extract and lavender oil for use in the treatment of sleep disorders
Publication Date: 2019.07.23 DR WILLMAR SCHWABE GMBH & CO
  • US10357530B2 patent drawing
  • US10357530B2 patent drawing
  • US10357530B2 patent drawing

AI summary

The present invention relates to a combination of valerian root extract and lavender oil treating of sleep disorders, as well as to a combination of preparation comprising valerian root extract and lavender oil.