Vanillin Cosmetic Composition with Sequestering Agent

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Solution Overview

Problem

There is a need for novel ingredients or mixtures that are effective in antimicrobial protection of cosmetic compositions, stable over time, and do not change appearance or color, especially at elevated temperatures, to prevent microbial growth and maintain product integrity.

Innovation Solution

A composition comprising water, at least one (C1-C6)(alkyl)vanillin, a sequestering agent such as the salts of formula (I) or ethylene diamine disuccinic acid, and optionally additional antimicrobials like C2 to C6 alkanols or non-ionic surfactants, which provides marked antimicrobial efficacy and stability.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If vanillin is used in cosmetic compositions for antimicrobial protection, then antimicrobial efficacy is improved, but color stability deteriorates over time at elevated temperatures

Engineering Contradiction:
Improveantimicrobial efficacyVSAvoidcolor stability
Core Design Contradiction:
ReliabilityVSStability of the object's composition

Solution Approach 1:

The patent introduces a sequestering agent as an intermediary substance that binds to metal ions and prevents them from catalyzing the oxidation of vanillin. This mediator protects vanillin from color degradation while preserving its antimicrobial activity, resolving the contradiction between efficacy and stability.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent creates a composite antimicrobial system combining vanillin with specific sequestering agents (such as EDTA or DTPA). This composite formulation maintains the antimicrobial benefits of vanillin while the sequestering agent prevents color change through chelation of metal ions, achieving both reliability and stability.

Inventive Principle:
Principle #40Composite materials

2Reliability

If preservative agents are added to prevent microbial growth, then microbial protection is improved, but product stability and compatibility may deteriorate

Engineering Contradiction:
Improvemicrobial protectionVSAvoidproduct stability
Core Design Contradiction:
ReliabilityVSStability of the object's composition

Solution Approach 1:

The patent optimizes the concentration parameters of vanillin and sequestering agents to achieve effective microbial protection while maintaining product stability. By carefully controlling the ratio and amount of each component, the formulation prevents microbial growth without compromising compatibility or causing unwanted chemical reactions.

Inventive Principle:
Principle #35Parameter changes

3Reliability

If multiple antimicrobials are combined to enhance protection, then antimicrobial efficacy is improved, but formulation complexity and potential interactions worsen

Engineering Contradiction:
Improveantimicrobial efficacyVSAvoidformulation complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent merges vanillin with sequestering agents in a unified formulation that achieves synergistic antimicrobial effect. This combination approach enhances protection while the sequestering agent simultaneously stabilizes the formulation, reducing the need for additional separate components and simplifying the overall structure.

Inventive Principle:
Principle #5Merging (Combining)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The described mixture exhibits excellent antimicrobial activity, remaining stable and odor-free over several weeks or months, even at temperatures between 37° C and 45° C, effectively preventing the growth of bacteria, yeasts, and molds.

Implementation Method 1

at least one sequestering agent selected from the salts of formula (I) such as defined hereinafter, and ethylene diamine disuccinic acid and the salts thereof

Methodology Applied
Scientific EffectChelation:

Implementation Method 2

The described mixture exhibits excellent antimicrobial activity, remaining stable and odor-free over several weeks or months, even at temperatures between 37° C and 45° C, effectively preventing the growth of bacteria, yeasts, and molds

Methodology Applied
Scientific EffectAntimicrobial action:

Data Source

PatentUS20250049662A1Aqueous cosmetic composition comprising vanillin or one of its derivatives, a specific sequestering agent, and possibly at least one additional antimicrobial
Publication Date: 2025.02.13 LOREAL SA
  • US20250049662A1 patent drawing
  • US20250049662A1 patent drawing
  • US20250049662A1 patent drawing

AI summary

The present invention relates to a composition, in particular cosmetic, comprising water and:i) at least one (C1-C6)(alkyl)vanillin, one of the organic or mineral basic salts thereof, or one of the solvates thereof such as hydrates;ii) at least one sequestering agent selected from the salts of formula (I) as well as the solvates thereof such as hydrates, and ethylene diamine disuccinic acid and the salts thereof, andiii) optionally at least one additional antimicrobial, preferably selected from C2 to C6 alkanols, C2 to C10 polyols, surfactants in particular non-ionic and mixtures thereof.