Variable-Density Stent Structure for Emboli Retention in Thrombectomy

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Solution Overview

Problem

Existing thrombectomy devices face challenges during procedures with antegrade blood flow, where engaged emboli can become dislodged due to blood flow's water-hammer effect, leading to incomplete removal or device failure.

Innovation Solution

The development of stenting devices with adjustable flexibility and varying density, featuring a distal tip that can be configured with a closed or porous end, designed for vessel diameters of specific arteries and optimized for improved access, placement, and embolus removal.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If a mechanical thrombectomy device is used during antegrade blood flow, then emboli can be captured and removed, but the water-hammer effect of blood flow can dislodge the emboli from the device

Engineering Contradiction:
Improveemboli retentionVSAvoidwater-hammer effect
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent applies parameter changes by varying the density of the stent structure along its length, creating regions of different radial strength to balance emboli retention and blood flow dynamics. The distal portion has lower density for flexibility and reduced water-hammer effect, while the proximal portion has higher density for secure emboli capture.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent implements local quality by creating non-uniform density distribution within the stent structure. Different segments of the stent have different material densities, allowing the distal tip to be more compliant with blood flow while the proximal segments provide stronger retention forces for emboli.

Inventive Principle:
Principle #3Local quality

2Reliability

If the stent density is increased to improve emboli retention, then the device becomes less flexible and harder to navigate through vessels

Engineering Contradiction:
Improveemboli retentionVSAvoiddevice flexibility
Core Design Contradiction:
ReliabilityVSEase of operation

Solution Approach 1:

The patent applies local quality by creating non-uniform density distribution within the stent structure. Different segments of the stent have different material densities, allowing the distal tip to be more compliant with blood flow while the proximal segments provide stronger retention forces for emboli.

Inventive Principle:
Principle #3Local quality

Solution Approach 2:

The patent implements segmentation by dividing the stent into distinct density zones - a less dense distal portion for navigation and flexibility, and a more dense proximal portion for emboli retention, effectively segmenting the functional requirements along the device length.

Inventive Principle:
Principle #1Segmentation

Data Source

PatentUS20250152388A1Novel enhanced stent making methods & applications of the same within vascular system needing the same
Publication Date: 2025.05.15 M4D LLC
  • US20250152388A1 patent drawing
  • US20250152388A1 patent drawing
  • US20250152388A1 patent drawing

AI summary

Improved stenting systems allow better placement without issues and placement, for example in the carotid arteries more facilely and rely during deployment than prior art.