Variable Volume Reservoir Gas Inlet for Isotope Ratio Spectrometer

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Solution Overview

Problem

Isotope ratio spectrometers face challenges in minimizing fractionation during analyte gas transfer, particularly in isotope ratio optical spectrometry, where the entire sample is required for analysis, leading to diffusion issues and reduced precision due to the need for high gas loads and carrier gases like dry air, which affects mixing and isotope signature preservation.

Innovation Solution

A gas inlet system with a variable volume reservoir and open split configuration is employed to manage gas flow and pressure, allowing for controlled analyte delivery, buffering pulsed supplies, and optimizing signal intensity within the spectrometer's measurement range, enabling constant or quasi-constant gas flow and pressure, and improving mixing with a carrier gas.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If the entire sample is transferred into the laser cell for IROS analysis, then the measurement can be performed, but diffusion occurs at the boundary between carrier gas and analyte leading to fractionation and reduced precision

Engineering Contradiction:
Improveisotope ratio measurement precisionVSAvoidfractionation during gas transfer
Core Design Contradiction:
Measurement precisionVSObject-generated harmful factors

Solution Approach 1:

The invention employs a dynamic flow control system that adjusts carrier gas flow rates during the transfer process. By varying the flow rate dynamically, the system minimizes diffusion time at the carrier gas-analyte boundary, thereby reducing fractionation while ensuring complete sample transfer to the laser cell for accurate isotope ratio measurement

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The system changes physical parameters such as pressure, temperature, and flow rate during the gas transfer process. By optimizing these parameters, the invention reduces diffusion effects at the gas boundary while maintaining complete sample transfer, thus minimizing fractionation and improving measurement precision

Inventive Principle:
Principle #35Parameter changes

2Measurement precision

If high gas loads are used in IROS to ensure complete sample transfer, then the entire sample can be analyzed, but the dynamic range is exceeded and signal linearity deteriorates

Engineering Contradiction:
Improveisotope ratio measurement precisionVSAvoidsignal linearity and dynamic range
Core Design Contradiction:
Measurement precisionVSDifficulty of detecting and measuring

Solution Approach 1:

The invention uses dynamic flow modulation to control the rate of sample transfer into the laser cell. By adjusting the carrier gas flow dynamically during injection, the system distributes the gas load over time, preventing dynamic range exceedance while ensuring complete sample transfer for accurate measurement

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The system employs periodic or pulsed carrier gas flow during sample introduction. This periodic action allows the sample to be transferred in controlled increments, maintaining signal linearity within the dynamic range while ensuring the entire sample is ultimately analyzed for precise isotope ratio determination

Inventive Principle:
Principle #19Periodic action

3Productivity

If pulsed analyte supply is used in IROS, then the measurement can be performed, but the signal intensity varies and precision is reduced

Engineering Contradiction:
Improvesample analysis throughputVSAvoidisotope ratio measurement precision
Core Design Contradiction:
ProductivityVSMeasurement precision

Solution Approach 1:

The invention employs a dynamic flow control system that responds to detected analyte pulses by adjusting carrier gas flow rates. This dynamic adjustment stabilizes the signal intensity during pulsed supply, maintaining measurement precision while preserving the productivity benefits of pulsed sampling

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The system uses feedback control where the detector signal is monitored in real-time and used to adjust the carrier gas flow. This feedback mechanism compensates for variations in pulsed analyte supply, stabilizing signal intensity and maintaining precision while allowing continuous operation and high throughput

Inventive Principle:
Principle #23Feedback

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This solution minimizes fractionation, enhances precision by maintaining constant analyte flow and pressure, and extends the dynamic range of the spectrometer, addressing the limitations of existing systems in handling high gas loads and carrier gases.

Implementation Method 1

the diffusion coefficient of CO2 in air is 0.16cm2/s... the transfer of the substance into the laser cell without fractionation (i.e. modification of the isotope signature) is demanding

Methodology Applied
Scientific EffectDiffusion: Diffusion

Implementation Method 2

Isotope ratio optical (usually infrared) spectrometry (IROS) is a more recently developed technique for isotope ratio analysis. Here, photo absorption by H2O molecules is measured and the isotopologies of H2O are calculated by spectroscopy

Methodology Applied
Scientific EffectPhoto absorption: Absorption (EM radiation)

Data Source

PatentEP3066449B1Gas inlet system for isotope ratio spectrometer
Publication Date: 2021.06.16 THERMO FISHER SCI BREMEN
  • EP3066449B1 patent drawingFigure 1
  • EP3066449B1 patent drawingFigure 2~3
  • EP3066449B1 patent drawingFigure 4~5

AI summary

A gas inlet system 20 for an isotope ratio spectrometer 1 and a method for coupling analyte gas to an isotope ratio spectrometer 1 are disclosed. A variable volume reservoir 5 is located between a supply of analyte gas 9,11 and a spectrometer 1. The reservoir's internal volume is controllably adjusted at a predetermined rate to generate a defined flow of analyte gas or mixture to or from the reservoir 5. Analyte gas and carrier gas are taken up by the reservoir 5 on increasing the reservoir's internal volume and then expelled from the reservoir to the spectrometer 1 on decreasing the reservoir's internal volume. An open split 3,8 can be used together with the reservoir 5 to facilitate splitting away and hence dilution of analyte within the reservoir 5. A method for cleaning the gas inlet system 20 is provided, which involves flushing the system with carrier gas.