Large-Bore Vascular Closure with Everted Tissue Stapling

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Solution Overview

Problem

Existing medical devices and methods for closing and sealing punctures in tissue and blood vessels are inadequate, requiring improved alternatives for efficient and effective closure.

Innovation Solution

A vascular closure system comprising an introducer sheath with a lumen and a shaping sheath having a split distal portion that everts tissue, combined with a stapler for deploying staples to secure the everted tissue, ensuring a transverse seam closure.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If existing medical devices and methods are used to close punctures in tissue and blood vessels, then the closure function is provided, but the effectiveness and efficiency are inadequate

Engineering Contradiction:
Improveclosure effectivenessVSAvoiddevice structure
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The closure device is divided into multiple functional segments: a delivery catheter for insertion, a shaping sheath with radially expandable elements for tissue engagement, and a closure mechanism with deployable anchors or staples. This segmentation allows each component to perform its specific function optimally while maintaining overall system effectiveness for closing vascular access sites

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The closure device employs a nested structure where the closure mechanism (anchors or staples) is contained within the shaping sheath, which itself is delivered through the introducer sheath. This nested configuration enables compact delivery through small punctures while allowing sequential deployment of components to achieve reliable closure without requiring overly complex external structures

Inventive Principle:
Principle #7Nested doll (Nesting)

2Device complexity

If a closure device is designed to be simple, then the device complexity is reduced, but the closure effectiveness and sealing capability are compromised

Engineering Contradiction:
Improvedevice structureVSAvoidsealing capability
Core Design Contradiction:
Device complexityVSReliability

Solution Approach 1:

The shaping sheath incorporates radially expandable elements at its distal end that can be selectively deployed to engage with the vessel wall tissue. This localized structural feature provides enhanced sealing capability at the critical closure site without requiring the entire sheath structure to be complex, thus maintaining simplicity elsewhere while ensuring effective sealing where needed

Inventive Principle:
Principle #3Local quality

Solution Approach 2:

The closure device performs preliminary actions by first deploying the shaping sheath with expandable elements to engage and shape the tissue, creating a prepared configuration before the actual closure mechanism (anchors or staples) is deployed. This preliminary tissue engagement and shaping ensures that the subsequent closure action is more effective and reliable, achieving good sealing without requiring an overly complex single-step device

Inventive Principle:
Principle #10Preliminary action

Data Source

PatentEP3515319B1Large bore vascular closure system
Publication Date: 2025.11.26 BOSTON SCIENTIFIC SCIMED INC
  • EP3515319B1 patent drawingFigure 1
  • EP3515319B1 patent drawingFigure 2
  • EP3515319B1 patent drawingFigure 3

AI summary

A vascular closure system for sealing an opening in a blood vessel may include an introducer sheath extending through the opening, the introducer sheath having a lumen extending through the introducer sheath, wherein partial withdrawal of the introducer sheath from the opening everts tissue of the blood vessel at the opening, and a shaping sheath slidably disposed over the introducer sheath, the shaping sheath having a split distal portion configured to engage the everted tissue.