Vascular Hub Loading Using Density-Stratified Fluid Injection

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Solution Overview

Problem

Existing vascular device loading methods face challenges in preventing premature hardening of liquid embolics due to mixing with other fluids, leading to increased risk of catheter rupture and operator strain.

Innovation Solution

A method involving precise orientation and positioning of syringes relative to vascular device hubs based on fluid densities to avoid mixing and channeling, using a sequence of fluid injections with different densities to minimize premature embolic hardening.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Adaptability or versatility

If multiple fluids are delivered through a single catheter and syringe assembly, then the treatment of various medical conditions is improved, but mixing between fluids occurs causing premature hardening of the embolic

Engineering Contradiction:
Improvedelivery of multiple fluidsVSAvoidpremature hardening risk
Core Design Contradiction:
Adaptability or versatilityVSReliability

Solution Approach 1:

The catheter system is segmented into multiple lumens (first lumen and second lumen) that remain separate throughout the delivery system. This allows multiple fluids to be delivered simultaneously or sequentially without mixing, preventing premature hardening while maintaining the ability to treat various medical conditions with different fluid combinations.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

A hub assembly acts as an intermediary component that receives multiple syringes and directs their contents through separate catheter lumens. The hub maintains fluid separation while enabling coordinated delivery of multiple fluids to the target site, resolving the contradiction between versatile multi-fluid delivery and prevention of premature mixing.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Device complexity

If fluids are injected sequentially through the same catheter, then the procedure is simplified, but excessive pressure is exerted on the equipment and biological subject

Engineering Contradiction:
Improveinjection procedureVSAvoidexcessive pressure
Core Design Contradiction:
Device complexityVSStress or pressure

Solution Approach 1:

The catheter is divided into multiple lumens that can be used simultaneously or independently. This segmentation allows pressure to be distributed across multiple pathways rather than concentrating force through a single lumen, reducing excessive pressure on equipment and biological tissues while maintaining procedural simplicity.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

Multiple fluid delivery functions are merged into a single catheter assembly with multiple lumens. This combining allows sequential or simultaneous injection through the same catheter structure without requiring multiple separate catheter insertions, simplifying the procedure while distributing pressure loads across multiple lumens.

Inventive Principle:
Principle #5Merging (Combining)

3Adaptability or versatility

If multiple fluid injections are performed manually, then the procedure is flexible, but operator strain or fatigue increases

Engineering Contradiction:
Improveinjection flexibilityVSAvoidoperator strain
Core Design Contradiction:
Adaptability or versatilityVSEase of operation

Solution Approach 1:

Multiple syringe injection functions are merged into a single hub assembly that can receive and coordinate multiple syringes. This integration maintains the flexibility to perform multiple fluid injections with different medications while reducing operator strain by providing a unified interface for managing multiple fluid deliveries.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The hub assembly serves multiple functions: receiving different syringes, directing fluids through separate catheter lumens, and enabling coordinated delivery of multiple fluids. This multi-functionality maintains procedural flexibility while simplifying operator interaction and reducing fatigue associated with managing multiple separate injection systems.

Inventive Principle:
Principle #6Universality (Multi-functionality)

4Quantity of substance

If larger volumes of fluids are injected to ensure adequate delivery, then the target site coverage is improved, but the risk of premature hardening increases

Engineering Contradiction:
Improvefluid volumeVSAvoidpremature hardening risk
Core Design Contradiction:
Quantity of substanceVSReliability

Solution Approach 1:

The fluid delivery system is segmented into separate lumens that prevent mixing. This allows larger volumes of each individual fluid to be injected without increasing premature hardening risk, as each fluid maintains its separation throughout the delivery pathway. The segmentation enables adequate target site coverage with larger volumes while preserving fluid integrity.

Inventive Principle:
Principle #1Segmentation

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Reduces the risk of premature embolic hardening and catheter rupture by up to 50%, while improving delivery efficiency and reducing operator strain.

Implementation Method 1

orienting the first syringe at a first elevation relative to the vascular device hub to place a denser one of the first liquid and the second liquid below a less dense one

Methodology Applied
Scientific EffectDensity stratification: Density Gradient

Data Source

PatentUS20250387556A1Vascular device loading
Publication Date: 2025.12.25 MICROVENTION INC
  • US20250387556A1 patent drawing
  • US20250387556A1 patent drawing
  • US20250387556A1 patent drawing

AI summary

Vascular device loading may be provided by loading a first liquid having a first density into a vascular device hub having an internal volume flowably connected between a syringe port and a cannula port; connecting a first syringe loaded with a second liquid to the syringe port, wherein the second liquid has a second density different than the first density; orienting the first syringe at a first elevation relative to the vascular device hub to place a denser one of the first liquid and the second liquid below a less dense one of the first liquid and the second liquid; and injecting, from the first syringe into the vascular device hub, the second liquid to eject the first liquid from the vascular device hub via the cannula port.