Vascular Lesion Detection Using Trendlines and Reference Points

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Solution Overview

Problem

Existing methods for detecting calcified lesions in vascular imaging, such as X-ray angiography, lack the ability to accurately identify and quantify multiple lesions and require manual analysis, which can be challenging for analysts without medical experience.

Innovation Solution

An electronic device that automates the segmentation and quantitative analysis of vascular images by calculating trendlines from medical images, identifying lesion candidates, and determining lesion sites using reference points and regression analysis to enhance detection accuracy.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If manual analysis of vascular images is performed, then flexibility and adaptability are maintained, but analysis time and complexity increase significantly

Engineering Contradiction:
Improvelesion detection speedVSAvoidautomated analysis system complexity
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The automated analysis system segments the vascular image into multiple vessel segments based on centerline extraction and branching points. Each segment is independently analyzed for lesion detection, allowing parallel processing and reducing overall analysis time while maintaining systematic complexity management through modular segmentation.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The system performs preliminary actions by pre-processing the vascular image to extract the centerline, identify branching points, and segment vessels before actual lesion detection. This preliminary structuring enables faster subsequent analysis and reduces the complexity of the main detection task by organizing data in advance.

Inventive Principle:
Principle #10Preliminary action

2Loss of time

If automated lesion detection is implemented, then analysis time is reduced, but measurement precision may be compromised

Engineering Contradiction:
Improvelesion detection timeVSAvoidlesion identification accuracy
Core Design Contradiction:
Loss of timeVSMeasurement precision

Solution Approach 1:

The system implements feedback mechanisms by comparing detected lesion candidates against multiple criteria including diameter reduction thresholds, trendline deviations, and reference point comparisons. This multi-layered verification provides feedback loops that refine detection accuracy while maintaining automated processing speed.

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The system changes and compares multiple parameters simultaneously - vessel diameter, diameter reduction ratio, trendline slope, and position relative to reference points. By monitoring multiple parameters rather than a single metric, the system achieves both speed and precision in automated lesion detection.

Inventive Principle:
Principle #35Parameter changes

3Loss of information

If multiple lesions are detected and visualized, then diagnostic completeness is improved, but image complexity and difficulty of interpretation increase

Engineering Contradiction:
Improvelesion information completenessVSAvoidvisualization system complexity
Core Design Contradiction:
Loss of informationVSDevice complexity

Solution Approach 1:

The system adds another dimension to the visualization by overlaying trendlines that show diameter changes along the vessel length. This dimensional addition allows multiple lesions to be visualized simultaneously with their severity and position clearly indicated, improving diagnostic completeness without overwhelming the viewer with raw data.

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

Solution Approach 2:

The system uses color coding to differentiate between normal vessels, lesion candidates, and confirmed lesions. This visual encoding allows multiple lesions to be quickly identified and distinguished by color rather than requiring detailed analysis of each individual marker, reducing interpretation complexity while maintaining information completeness.

Inventive Principle:
Principle #32Color changes

Data Source

PatentUS12518384B2Lesion determination method and device
Publication Date: 2026.01.06 MEDIPIXEL INC
  • US12518384B2 patent drawing
  • US12518384B2 patent drawing
  • US12518384B2 patent drawing

AI summary

An electronic device according to one embodiment can acquire a first trendline related to vessels from a medical image; determine lesion candidates among the vessels on the basis of the first trendline; acquire a second trendline on the basis of a reference point selected in the vicinity of the lesion candidates; and determine a lesion site among the lesion candidates on the basis of the acquired second trendline.