Vascular Servovalves for Continuous-Flow Graft Transfer
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Solution Overview
Problem
Existing surgical procedures for organ transplantation and vascular repairs often require interrupting blood flow, leading to complications such as ischemia, which can cause graft failure, infection, and cancer, and lack the ability to accommodate patient growth.
Innovation Solution
The use of vascular servovalves and valves that allow continuous, non-invasive control over blood flow diversion, enabling seamless organ transfer and repair without interrupting circulation, using a fully implanted disorder response system for precise medication targeting and monitoring.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If traditional surgical procedures are used for organ transplantation and vascular repairs, then the procedures can be performed with existing surgical techniques, but blood flow must be interrupted causing ischemia and related complications
Solution Approach 1:
The patent applies the continuity of useful action principle by implementing a side-entry valve system that allows blood flow to continue uninterrupted through the native vessel while simultaneously enabling diversion to a graft. The valve remains open during operation, eliminating the need to stop blood flow for anastomosis, thus preventing ischemia and improving graft survival.
Solution Approach 2:
The side-entry valve acts as an intermediary device that mediates between the native vessel and the graft. It provides a controlled interface that allows blood to be diverted from the native vessel to the graft without interrupting flow in the native vessel, thereby eliminating ischemia while enabling the transplantation procedure.
2Ease of manufacture
If traditional surgical procedures are used, then the procedures can be completed with standard techniques, but they require interrupting blood flow which leads to complications such as infection and cancer
Solution Approach 1:
By maintaining continuous blood flow through the side-entry valve during the procedure, the patent eliminates the ischemia-reperfusion injury that occurs with traditional interrupted flow techniques. This continuous circulation prevents the development of infection and cancer risks associated with prolonged surgical exposure and tissue damage.
3Adaptability or versatility
If conventional vascular repair methods are used, then the procedures can be performed with standard surgical techniques, but they cannot accommodate patient growth
Solution Approach 1:
The patent incorporates a dynamic component by using a self-expanding mesh structure in the valve prosthesis. This mesh can expand automatically in response to pressure differential across the valve, adapting to changes in vessel size due to patient growth without requiring surgical intervention.
Solution Approach 2:
The self-expanding mesh structure provides self-service functionality by automatically adjusting to accommodate patient growth through pressure-driven expansion. This eliminates the need for complex surgical adjustments or interventions to adapt the device to changing vessel dimensions.
4Measurement precision
If a fully implanted disorder response system is used for precise medication targeting, then medication delivery precision is improved, but device complexity increases
Solution Approach 1:
The patent uses an implanted pump and catheter system as intermediaries to deliver medication precisely to the valve site. The pump acts as a controlled intermediary that can be programmed to release specific medications at controlled rates, while the catheter serves as a targeted delivery pathway, achieving precise medication delivery without requiring complex surgical procedures.
Data Source
AI summary
Set forth are vascular valves and servovalves and methods of using the same that may be positioned in the circulatory system without interrupting blood flow to facilitate solid organ transplantation so as to reduce graft organ anoxia and degradation before and after harvesting and storage, thereby minimizing late-term cardiac allograft vasculopathy as a major cause of graft failure. Along the urinary tract, bypassing bladder-generated urge sensation by diverting urine directly from the ureters to a neobladder or collection bag alleviates intractable incontinence, nocturia, urethral syndrome, overactive bladder, dysuria, or frequency. Where the lower tract is missing, a prosthesis can thwart disease and preclude the degenerative metaplastic transition to carcinoma risked when gut is used to construct a conduit for urine, a neobladder, and/or high-maintenance stoma. Druglines to valves and servovalves can directly pipeline-target medication to nidi, anastomoses, or any other trouble spots.