Vasocompression Head Covering for Chemotherapy Hair Protection

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Solution Overview

Problem

Current methods for mitigating chemotherapy-induced alopecia, hair follicle death, and anagen effluvium are inadequate and vary in efficacy, with scalp cooling not being effective in all cases.

Innovation Solution

A head covering that induces vasocompression by blocking the arterial blood supply to the scalp using expandable bladders and pressure sources to prevent chemotherapeutic agents from reaching hair follicles, combined with optional cooling and monitoring features.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If scalp cooling is used to prevent chemotherapy-induced alopecia, then blood flow to the scalp is reduced, but the efficacy varies from person to person and does not work in all cases

Engineering Contradiction:
Improveefficacy of chemotherapy-induced alopecia preventionVSAvoidindividual response variability
Core Design Contradiction:
ReliabilityVSAdaptability or versatility

Solution Approach 1:

The patent changes the physical parameter from temperature-based cooling to pressure-based vasocompression. By applying mechanical compression to the scalp, the device directly blocks blood flow without relying on thermal mechanisms, thereby achieving more reliable and consistent prevention of chemotherapy-induced alopecia across different individuals.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent replaces the thermal cooling system with a mechanical compression system. Instead of using cold to constrict blood vessels, the device uses inflatable bladders that mechanically compress the scalp and underlying blood vessels, providing a more direct and reliable method of blocking chemotherapeutic agent delivery to hair follicles.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

2Reliability

If vasocompression is applied to block arterial blood supply to the scalp, then chemotherapeutic agents are prevented from reaching hair follicles, but the device complexity increases with expandable bladders and pressure sources

Engineering Contradiction:
Improveblocking of chemotherapeutic agent delivery to hair folliclesVSAvoidstructure of head covering with vasocompression elements
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent divides the scalp into multiple treatment zones using separate inflatable bladders positioned at different locations. Each bladder can be independently inflated and deflated to target specific vascular regions, allowing customized vasocompression that blocks chemotherapeutic agents to hair follicles while managing complexity through modular design.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent employs dynamically adjustable pressure through inflatable bladders that can be inflated and deflated as needed. This dynamic system allows the device to adapt to different patients and treatment phases, providing reliable vasocompression when required while reducing complexity through on-demand activation rather than continuous operation.

Inventive Principle:
Principle #15Dynamics

3Reliability

If continuous vasocompression is maintained during chemotherapy, then hair follicles are protected from chemotherapeutic agents, but patient comfort and circulation may be compromised

Engineering Contradiction:
Improveprotection of hair follicles from chemotherapeutic agentsVSAvoidpatient discomfort and circulation restrictions
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent implements periodic inflation and deflation cycles of the vasocompression bladders rather than continuous compression. This periodic action maintains protection of hair follicles during chemotherapy administration while allowing circulation to recover during deflation phases, thereby reducing patient discomfort and minimizing circulation restrictions.

Inventive Principle:
Principle #19Periodic action

Solution Approach 2:

The patent ensures continuous protection of hair follicles by maintaining vasocompression throughout the chemotherapy administration period. The system can be configured to provide continuous compression during the critical chemotherapeutic delivery window while allowing brief relief periods, ensuring useful action continues without compromising patient welfare.

Inventive Principle:
Principle #20Continuity of useful action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The head covering effectively reduces the delivery of chemotherapeutic agents to hair follicles, minimizing hair loss and follicle death by maintaining a controlled vasocompression to protect the scalp and eyebrows during chemotherapy sessions.

Implementation Method 1

at least one vasocompression element within the outer shell, wherein the at least one vasocompression element is configured to block off the arterial blood supply to the scalp

Methodology Applied
Scientific EffectVasocompression: Compression

Implementation Method 2

a cooling gas source in communication with the liner or the at least one vasocompression element wherein a portion of the liner or a portion of the at least one vasocompression element is adapted to provide cooling to an interior portion of the head covering

Methodology Applied
Scientific EffectCooling: Cooling

Data Source

PatentEP4171459B1Vasocompression devices and methods of delivering vasocompression therapy to a patient undergoing chemotherapy treatment
Publication Date: 2025.09.10 GUANGZHOU FOLLISAVE TECH DEV LTD
  • EP4171459B1 patent drawingFigure 1A~2B
  • EP4171459B1 patent drawingFigure 3A~4
  • EP4171459B1 patent drawingFigure 5A~5D

AI summary

Various devices and methods useful for providing vasocompression to a patient who is undergoing chemotherapy treatment.