Venous Thrombectomy Catheter With Cutting and Capture for Chronic Thrombus
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Solution Overview
Problem
Existing catheter-based thrombectomy devices have limited success in removing chronic thrombus due to its transformation into a tougher fibrin and collagen structure, which is firmly adhered to the vein wall, and venous synechiae prevent optimal treatment by balloon angioplasty or stenting.
Innovation Solution
A device with an elongated member featuring a cutting portion and a capturing portion, where the cutting portion radially deploys to cut obstructive material and the capturing portion collects dislodged material, allowing for independent deployment and collection of chronic thrombus.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If catheter-based thrombectomy devices are used to remove chronic thrombus, then the procedure can be performed, but the success rate is limited due to the tough fibrin and collagen structure of chronic thrombus that is firmly adhered to the vein wall
Solution Approach 1:
The device divides the thrombus removal function into two separate portions: a cutting portion with cutting elements that fragment the thrombus, and a capturing portion that collects the dislodged material. This segmentation allows the cutting elements to effectively break apart the tough chronic thrombus while the capturing portion ensures complete removal, thereby improving success rate without increasing adhesion strength requirements
Solution Approach 2:
The cutting elements are designed to be deployable from a low-profile collapsed state during delivery to an expanded state at the treatment site where they actively cut and fragment the thrombus. This dynamic deployment allows the device to adapt to the tough adhesion of chronic thrombus by activating cutting action only when needed, improving removal success while maintaining safe delivery characteristics
2Adaptability or versatility
If venous synechiae are present, then chronic thrombus can form, but balloon angioplasty or stenting cannot be optimally treated due to the fibrous structures preventing permanent stretching of the vessel wall
Solution Approach 1:
The device extracts and removes the fibrous synechiae and thrombus material from the vein wall through the cutting and capturing mechanism. By completely removing the obstructive material and fibrous structures, the device restores vessel patency without requiring the vessel wall to be permanently stretched or modified, thereby providing treatment adaptability while preserving vessel wall stability and flexibility
Solution Approach 2:
The device replaces the mechanical stretching and expanding mechanisms of balloon angioplasty and stenting with a cutting and capturing mechanism. Instead of forcing the vessel wall to expand permanently (which synechiae prevent), the device mechanically cuts and removes the fibrous obstacles, allowing natural vessel recovery without compromising wall flexibility or requiring permanent structural modification
Data Source
AI summary
According to some embodiments, the present technology includes device for removing obstructive material from a blood vessel lumen. For example, the device can comprise an elongated member, a cutting portion carried by a distal region of the elongated member, and a capture portion carried by the distal region of the elongated member. The cutting portion can comprise a blade configured to separate at least a portion of the obstructive material from the blood vessel wall, and the capture portion can comprise a mesh structure configured to enmesh and/or capture at least a portion of the obstructive material.