Ventilator Breathing Phase Synchronization to Reduce Hypercapnia

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Solution Overview

Problem

Subjects undergoing respiratory therapy, particularly mechanical ventilation, often experience incomplete exhalation, leading to discomfort and medical issues like hypercapnia and air trapping, due to the challenge of synchronizing inhalation and exhalation phases effectively.

Innovation Solution

A system comprising a pressure generator, sensors, and processors that adjust the pressurized flow of breathable gas based on breathing phase timing and parameters, ensuring inspiratory and expiratory positive airway pressures are applied appropriately, determining when a subject has completed exhalation to facilitate complete exhalation and reduce hypercapnia.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If a pressurized flow of breathable gas is delivered to the airway using a mechanical ventilator, then respiratory support is provided to the subject, but incomplete exhalation occurs leading to hypercapnia and air trapping

Engineering Contradiction:
Improverespiratory support effectivenessVSAvoidhypercapnia and air trapping
Core Design Contradiction:
ReliabilityVSObject-generated harmful factors

Solution Approach 1:

The system continuously monitors the subject's breathing cycle using sensors that detect inhalation and exhalation phases. This feedback information is used to dynamically adjust the timing and duration of pressurized gas delivery, ensuring that each exhalation is complete before the next inhalation begins, thereby preventing air trapping andhypercapnia while maintaining effective respiratory support

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The mechanical ventilator dynamically adapts its operation by adjusting the timing parameters of gas delivery based on real-time detection of the subject's breathing cycle. The system modifies the duration and timing of inspiratory and expiratory phases dynamically, rather than using fixed timing, to ensure complete exhalation and prevent harmful accumulation of CO2

Inventive Principle:
Principle #15Dynamics

2Object-affected harmful factors

If the timing of pressurized gas delivery is adjusted based on breathing phase detection, then complete exhalation is achieved reducinghypercapnia, but system complexity increases

Engineering Contradiction:
Improvehypercapnia reductionVSAvoidsystem complexity
Core Design Contradiction:
Object-affected harmful factorsVSDevice complexity

Solution Approach 1:

The system uses the subject's own breathing signals to automatically control the timing of gas delivery. The sensors detect the natural inhalation and exhalation phases, and this information directly controls the ventilator operation without requiring external intervention or complex manual programming, thereby reducing system complexity while achieving complete exhalation

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The system changes the timing parameters of gas delivery based on detected breathing phase transitions. By monitoring changes in breathing flow rate and volume parameters, the system automatically adjusts inspiratory and expiratory timing to ensure complete exhalation, achievinghypercapnia reduction through parameter adaptation rather than complex structural modifications

Inventive Principle:
Principle #35Parameter changes

Data Source

PatentUS11291786B2Reducing hypercapnic respiratory failure during mechanical ventilation
Publication Date: 2022.04.05 KONINKLIJKE PHILIPS NV
  • US11291786B2 patent drawing
  • US11291786B2 patent drawing
  • US11291786B2 patent drawing

AI summary

Systems and methods provide respiratory therapy to a subject through a pressurized flow of breathable gas. Timing and other characteristics of pressure and flow levels provided during inhalations and exhalations are adjusted in order to increase the volumetric rate of expulsion of CO2.