Noninvasive Ventricular-Arterial Coupling Measurement via Pulse Wave Velocity
Find Innovative SolutionsGenerate Solutions
Solution Overview
Problem
Current methods for monitoring stroke volume and cardiac output in clinical settings, such as pulse contour analysis and echocardiography, are invasive, have limited trending ability, and are not suitable for continuous real-time monitoring, especially in cardiac operating rooms and intensive care units.
Innovation Solution
A device and method using electrocardiogram and photoplethysmogram sensors to measure ventricular-arterial coupling by determining pulse wave travel distance and velocity, allowing for non-invasive, real-time estimation of stroke volume and cardiac output.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If invasive methods such as pulmonary artery catheter are used to monitor stroke volume and cardiac output, then measurement precision is improved, but device complexity and patient harm increase
Solution Approach 1:
The patent replaces invasive mechanical catheter-based measurement with non-invasive optical detection using photoplethysmogram sensors and ECG sensors to measure pulse wave velocity and estimate stroke volume, eliminating the need for pulmonary artery catheter insertion while maintaining measurement capability
Solution Approach 2:
The patent uses pulse wave velocity as an intermediary parameter to indirectly measure stroke volume and cardiac output, avoiding direct invasive measurement while providing accurate hemodynamic information through the relationship between pulse wave velocity, arterial compliance, and ventricular ejection
2Productivity
If conventional hemodynamic monitoring methods are used, then stroke volume and cardiac output can be estimated, but continuous real-time monitoring capability is limited
Solution Approach 1:
The patent enables continuous real-time monitoring by continuously measuring ECG and photoplethysmogram signals to calculate pulse wave velocity and derive stroke volume and cardiac output trends, providing uninterrupted hemodynamic data for clinical decision-making
Solution Approach 2:
The patent provides real-time feedback through continuous calculation of stroke volume and cardiac output from pulse wave velocity measurements, allowing dynamic adjustment of clinical interventions based on trending hemodynamic parameters
3Measurement precision
If echocardiography is used for stroke volume and cardiac output monitoring, then measurement accuracy is improved, but ease of operation and continuous monitoring are compromised
Solution Approach 1:
The patent employs automated algorithms that process ECG and photoplethysmogram signals to automatically calculate pulse wave velocity, stroke volume, and cardiac output without requiring operator interpretation or manual measurements, eliminating operator dependence while maintaining accuracy
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
Provides a non-invasive, real-time monitoring tool for assessing arterial vascular performance, enabling continuous measurement of stroke volume and cardiac output, improving patient management in clinical settings by optimizing ventricular-arterial coupling.
Implementation Method 1
The first input receives signals from a plurality of electrocardiogram sensors that are coupled to the subject at a plurality of first locations
Implementation Method 2
The second input receives signals from a plurality of photoplethysmogram sensors that are coupled to the subject at a plurality of second locations
Data Source
AI summary
A device for measuring a ventricular-arterial coupling of a subject includes first and second inputs. The first input receives signals from a plurality of electrocardiogram sensors that are coupled to the subject at a plurality of first locations. The second input receives signals from a plurality of photoplethysmogram sensors that are coupled to the subject at a plurality of second locations. The second locations are selected from the group consisting of a head of the subject, an arm of the subject, and a leg of the subject. The signals received from the electrocardiogram sensors and the signals received from the photoplethysmogram sensors are received simultaneously. The device also includes a monitor configured to display the signals from the electrocardiogram sensors and the signals from the photoplethysmogram sensors.