Ventricular Catheter Balloon Positioning for Cardiac Viability

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Solution Overview

Problem

Current systems fail to accurately assess cardiac function of donor hearts before transplantation, particularly in preventing damage during measurement and ensuring accurate prediction of post-transplant cardiac function, with existing methods being limited in application to humans and causing potential harm to the heart tissue.

Innovation Solution

A specialized catheter system with an inflatable balloon and expandable mesh, designed for insertion into the ventricles, which includes a pressure sensor and servo-controlled inflation device to measure cardiac viability without causing significant damage, allowing for separate evaluation of each ventricle's function and secure positioning within the heart.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If a measuring apparatus is inserted into the ventricular cavity to measure cardiac function, then cardiac function can be assessed, but the apparatus may be ejected during contraction causing damage to heart tissue

Engineering Contradiction:
Improvecardiac function assessmentVSAvoidheart tissue damage
Core Design Contradiction:
Measurement precisionVSObject-affected harmful factors

Solution Approach 1:

The catheter is positioned and secured in the ventricular cavity before cardiac contraction occurs. The operator positions the catheter tip against the ventricular wall and secures it before the heart begins beating, preventing ejection during contraction and avoiding tissue damage while enabling accurate pressure measurements

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The catheter acts as an intermediary device that transmits pressure information from the ventricular cavity to external measurement instruments without requiring direct fixation to the heart wall. The catheter's flexible structure allows it to follow ventricular wall motion and transmit pressure waves accurately while avoiding tissue damage

Inventive Principle:
Principle #24Intermediary (Mediator)

2Stability of the object's composition

If surgical fixation is used to prevent measuring apparatus ejection, then apparatus stability is improved, but labor increases and heart tissue may be damaged

Engineering Contradiction:
Improvemeasuring apparatus stabilityVSAvoidsurgical procedure complexity
Core Design Contradiction:
Stability of the object's compositionVSEase of manufacture

Solution Approach 1:

The catheter is designed to be self-retaining through its physical configuration rather than requiring external fixation. The catheter's shape and flexibility allow it to maintain position within the ventricular cavity by conforming to the chamber geometry and following wall motion, eliminating the need for surgical sutures or clips

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The catheter employs a flexible structure that can conform to the ventricular cavity shape and move with the heart wall during contraction. This flexibility allows the catheter to maintain stable positioning without rigid fixation, avoiding tissue damage while ensuring measurement stability

Inventive Principle:
Principle #30Flexible shells and thin films

3Ease of operation

If ventricles are not fully filled with blood, then measurement conditions are simplified, but air may be ejected through the aortic valve and coronary arteries causing damage

Engineering Contradiction:
Improvemeasurement setupVSAvoidair ejection damage
Core Design Contradiction:
Ease of operationVSObject-affected harmful factors

Solution Approach 1:

The system extracts and removes air from the ventricular cavity through the catheter before measurement begins. By actively removing air bubbles from the chamber, the system prevents air from being ejected through the aortic valve and coronary arteries during contraction, eliminating the harmful effect while maintaining simplified measurement conditions

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The system applies preliminary action to prevent air ejection damage before it can occur. By removing air from the ventricular cavity before cardiac contraction begins, the system pre-empts the potential harmful effect of air being forced through the aortic valve and coronary arteries during the measurement process

Inventive Principle:
Principle #9Preliminary anti-action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables accurate and non-damaging cardiac function assessment of donor hearts, preventing air ejection and ensuring secure positioning, thereby improving the prediction of post-transplant cardiac function and reducing the risk of heart tissue damage during measurement.

Implementation Method 1

a pressure sensor

Methodology Applied
Scientific EffectPressure sensing:

Implementation Method 2

The hollow body allows for fluid to be pumped out of the distal end, into the balloon

Methodology Applied
Scientific EffectFluid pressurization: Pressurisation

Data Source

PatentEP2981208B1Cardiac function evaluation system
Publication Date: 2022.09.07 ORGAN TRANSPORT PTY LTD
  • EP2981208B1 patent drawingFigure 1
  • EP2981208B1 patent drawingFigure 2
  • EP2981208B1 patent drawingFigure 3

AI summary

A device adapted for determining cardiac viability, wherein said device includes: a cannula having a hollow body and at least a distal end adapted for insertion into a heart and operator end for adapted for an operator to position the catheter in the ventricular apex and adapted for connection to a plumbing system; an inflatable balloon positioned near to the distal end in fluid communication with the hollow body to allow for selected inflation of the balloon, a controller adapted to calculate the viability of the heart from pressure data detected within cannula or balloon which is inflated to various degrees with an incompressible fluid.