VEP Measurement System Using Segmented Windmill Stimuli

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Solution Overview

Problem

Current methods for measuring visual evoked potentials (VEP) lack precision in assessing the health of the retina and visual pathway, particularly in diagnosing diseases affecting the macula and optic nerve.

Innovation Solution

A medical system comprising a display showing alternating windmill patterns with equidistant light and dark circular sectors, EEG electrodes to record brain activity, and an analyzing module to derive VEPs, allowing for precise analysis of retinal health by comparing amplitudes and latencies of VEP components with reference curves.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If conventional VEP measurement methods are used, then the measurement process is simple, but the precision in assessing retinal health and diagnosing macular/optic nerve diseases is insufficient

Engineering Contradiction:
Improveprecision in assessing retinal healthVSAvoidcomplexity of measurement system
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The visual stimulus is segmented into multiple discrete circular sectors (e.g., 8 sectors) that can be independently controlled in terms of luminance and position. This segmentation allows systematic variation of stimulus parameters to elicit different VEP components, thereby improving measurement precision for different retinal regions while maintaining a manageable system complexity through modular stimulus control

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The stimulus configuration is made dynamic by allowing real-time adjustment of circular sector parameters (luminance, position, size) during the measurement process. This dynamic adaptability enables the system to optimize stimulus presentation for different diagnostic conditions and patient responses, improving measurement precision without requiring permanently complex hardware

Inventive Principle:
Principle #15Dynamics

2Adaptability or versatility

If systematic variation of circular sectors is implemented, then diagnostic capabilities for retinal diseases are improved, but the complexity of stimulus control increases

Engineering Contradiction:
Improvediagnostic capabilitiesVSAvoidcomplexity of stimulus control
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The stimulus generation system is designed with multi-functionality to perform multiple diagnostic tasks using the same basic apparatus. The circular sector configuration can be varied to assess different retinal regions, disease conditions, and visual pathway functions, thereby improving diagnostic versatility while avoiding the need for multiple specialized devices

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The system improves diagnostic capabilities by systematically varying stimulus parameters (luminance contrast, circular sector size, position, and temporal frequency) to elicit different VEP components. These parameter changes allow differentiation between various retinal pathologies while being controlled through software rather than requiring complex hardware modifications

Inventive Principle:
Principle #35Parameter changes

3Loss of information

If windmill patterns with multiple circular sectors are used, then the analysis of neural activity is enhanced, but the complexity of data processing increases

Engineering Contradiction:
Improveinformation from neural activityVSAvoidcomplexity of data processing
Core Design Contradiction:
Loss of informationVSDevice complexity

Solution Approach 1:

The windmill pattern stimulus employs periodic rotation and luminance modulation at controlled frequencies to elicit periodic VEP responses. This periodic action allows synchronization of stimulus presentation with EEG recording, facilitating efficient extraction of VEP signals from neural activity data while reducing processing complexity through frequency-based signal separation

Inventive Principle:
Principle #19Periodic action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables accurate determination of retinal health by systematically varying the number and area of circular sectors, improving diagnostic capabilities for retinal diseases by correlating neural activity with visual stimulus responses.

Implementation Method 1

a display (2) for displaying images to be observed by the person with a single eye

Methodology Applied
Scientific EffectVisual stimulus detection:

Implementation Method 2

a plurality of electrodes (3) configured to be attached to the scalp of the person and to detect EEG signals indicative of electrical activity in the brain

Methodology Applied
Scientific EffectElectrical activity detection:

Implementation Method 3

an analyzing module (8), the analyzing module (8) being configured to derive from said EEG signals recorded by the EEG recording module (4) at least one visual evoked potential (VEP)

Methodology Applied
Scientific EffectSignal averaging:

Data Source

PatentUS20240225518A1Medical system and method for measuring visual evoked potentials (VEP) of a person
Publication Date: 2024.07.11 UNIVERSITY OF ZURICH
  • US20240225518A1 patent drawing
  • US20240225518A1 patent drawing
  • US20240225518A1 patent drawing

AI summary

The present invention relates to a medical system (20) for measuring visual evoked potentials (VEP) of a person, comprising a display (2) for displaying images to be observed by the person with a single eye, and an image generating module (1), the image generating module (1) being configured to cause the display (2) to display a sequence of images comprising a first image and a second image. The medical system (20) further comprises: a plurality of electrodes (3) configured to be attached to the scalp of the person and to detect EEG signals indicative of electrical activity in the brain of the person in response to observing said sequence of images displayed by the display (2), an EEG recording module (4) connected to said plurality of electrodes (3), the EEG recording module (4) being configured to record said EEG signals, and an analyzing module (8), the analyzing module (8) being configured to derive from said EEG signals recorded by the EEG recording module (4) at least one visual evoked potential (VEP).