Verbascoside Extract UV Absorption and Skin Protection

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Solution Overview

Problem

Existing sunscreens, both synthetic and natural, face challenges such as adverse skin reactions, environmental toxicity, and photo-stability issues, which affect their ability to provide broad-spectrum UV protection without frequent reapplication.

Innovation Solution

A composition containing an extract rich in verbascoside and its derivatives or structural analogs, derived from specific plants like sesame, Lippia citriodora, and Cistanche tubulosa, which effectively absorbs UV-A and UV-B radiation and maintains photo-stability.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If synthetic organic sunscreens are used to achieve UV protection, then UV-B or UV-A absorption is improved, but adverse skin reactions and environmental toxicity occur

Engineering Contradiction:

ImproveUV protection efficacyVSAvoidadverse skin reactions and environmental toxicity

Core Design Contradiction:

ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent extracts and utilizes naturally occurring verbascoside and its derivatives from plant sources (such as Lippia citriodora, Cistanche tubulosa, and other medicinal plants) to replace synthetic organic sunscreen filters. This extraction approach isolates the beneficial UV-absorbing compounds while eliminating the toxic effects associated with synthetic chemicals, thereby resolving the contradiction between UV protection efficacy and safety/environmental compatibility

Inventive Principle:

Principle #2Taking out (Extraction)

Solution Approach 2:

The patent changes the chemical composition parameters by substituting synthetic organic filters with natural phenolic compounds (verbascoside and its derivatives). This parameter change maintains the UV absorption capability while fundamentally altering the chemical nature of the sunscreen agents to be biocompatible and environmentally friendly, thus resolving the harmful effects without sacrificing protection efficacy

Inventive Principle:

Principle #35Parameter changes

2Object-affected harmful factors

If natural plant extracts are used as sunscreens, then environmental friendliness and skin safety are improved, but photo-stability and broad-spectrum UV protection are insufficient

Engineering Contradiction:

Improveenvironmental friendliness and skin safetyVSAvoidphoto-stability and broad-spectrum UV protection

Core Design Contradiction:

Object-affected harmful factorsVSReliability

Solution Approach 1:

The patent creates a composite sunscreen formulation by combining verbascoside with its derivatives and structural analogs (such as echinacoside, isoverbascoside, and other phenolic compounds). This composite approach synergistically enhances the photo-stability and broad-spectrum UV protection capability while maintaining the environmental friendliness and skin safety of natural plant extracts, thus resolving the contradiction between safety and protection efficacy

Inventive Principle:

Principle #40Composite materials

3Reliability

If high concentrations of synthetic sunscreens are applied to achieve high SPF values, then UV protection is improved, but frequency of reapplication increases due to photo-degradation

Engineering Contradiction:

ImproveSPF valueVSAvoidduration of UV protection

Core Design Contradiction:

ReliabilityVSDuration of action of stationary object

Solution Approach 1:

The patent ensures continuous UV protection by selecting verbascoside and its derivatives that possess high photo-stability and resistance to UV-induced degradation. These natural compounds maintain their protective action over extended periods without significant loss of efficacy, eliminating the need for frequent reapplication and thus resolving the contradiction between achieving high SPF values and maintaining prolonged protection duration

Inventive Principle:

Principle #20Continuity of useful action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The composition achieves high SPF values and excellent UVA/UVB protection, while being environmentally friendly and safe for human use, with enhanced photo-stability that reduces the need for frequent reapplication.

Implementation Method 1

verbascoside and its analogs effectively absorb broadband UV-B and UV-A radiation

Methodology Applied

Scientific EffectUV absorption: Absorption (EM radiation)

Implementation Method 2

they can prevent/inhibit free radical formation in the skin irradiated by UV-B and UV-A

Methodology Applied

Scientific EffectAntioxidant activity: Oxidation

Data Source

PatentUS20250032569A1Composition, in particular cosmetic formulation, comprising a verbascoside extract

Publication Date: 2025.01.30 MEDENA AG

AI summary

A composition, in particular a cosmetic formulation, comprising an extract containing verbascoside and/or derivatives thereof and/or structural analogs thereof, wherein the extract is prepared from aerial parts of plants selected from the group consisting of sesame plant (Sesamum indicum), Lippia citriodora, Haeberlea rhodopensis, Cistanche tubulosa, Syringa vulgaris, Aiuga reptens, Buddleija davidii, Verbena officinalis, and Olea europea or wherein the extract is prepared from cell callus cultures of said parts of plants.