Vertical Flow Loop Reactor for Methane Fermentation

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Solution Overview

Problem

Current methods for converting methane to higher-value hydrocarbons are hindered by low yields, poor selectivity, and high capital costs, particularly in small-scale operations, due to the Fischer-Tropsch process's inefficiencies and sensitivity to contaminants, limiting the adoption of gas-to-liquids processes and stranding methane sources.

Innovation Solution

The development of fermentation systems that efficiently transfer gaseous substrates like methane to microbial cultures, using C1 metabolizing microorganisms such as methanotrophs and methylotrophs, within loop reactors designed for enhanced mass transfer, allowing for the conversion of methane into higher-value products.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If Fischer-Tropsch process is used to convert methane to higher-order hydrocarbons, then conversion capability is achieved, but capital expenditure and scale requirements are excessively high

Engineering Contradiction:
Improvemethane conversion capabilityVSAvoidcapital expenditure and scale
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The patent segments the methane conversion process into two distinct stages: (1) gas-to-liquids conversion using C1-metabolizing microorganisms in aqueous phase, and (2) fermentation of the resulting liquid products. This segmentation allows each stage to be optimized independently, avoiding the need for massive integrated F-T plants while achieving economical production at smaller scales

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent introduces an intermediary substance - water-soluble liquid products (such as carboxylic acids, alcohols, or sugars) - that are produced by C1-metabolizing microorganisms from methane. These intermediaries serve as bridge compounds that can be easily transported and further processed through fermentation, eliminating the need for direct large-scale F-T synthesis infrastructure

Inventive Principle:
Principle #24Intermediary (Mediator)

2Productivity

If Fischer-Tropsch process is used for methane conversion, then hydrocarbon production is achieved, but yield and selectivity are low

Engineering Contradiction:
Improvehydrocarbon productionVSAvoidyield and selectivity
Core Design Contradiction:
ProductivityVSManufacturing precision

Solution Approach 1:

The patent employs C1-metabolizing microorganisms that naturally possess high selectivity in converting methane to specific liquid products through their metabolic pathways. The biological systems self-regulate the conversion process to produce desired products (such as carboxylic acids, alcohols, or sugars) with high selectivity, eliminating the need for complex catalyst design and process optimization required in F-T processes

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The patent changes the fundamental parameters of the conversion process by operating in aqueous phase at moderate temperatures and pressures, using biological catalysts instead of metallic F-T catalysts. This parameter change enables higher yields and selectivities through enzymatic control, while avoiding the low selectivity inherent in thermal F-T processes

Inventive Principle:
Principle #35Parameter changes

3Productivity

If C1-metabolizing microorganisms are used in conventional bioreactors, then methane conversion is achieved, but reactor footprint and costs are high

Engineering Contradiction:
Improvemethane conversionVSAvoidreactor footprint
Core Design Contradiction:
ProductivityVSArea of stationary object

Solution Approach 1:

The patent transitions from conventional horizontal bioreactor design to a vertical flow system where substrates and microorganisms move through a vertically oriented reaction column. This dimensional change increases the effective reaction volume per unit footprint, allowing higher productivity in a compact space while maintaining efficient mass transfer and mixing

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

These systems achieve higher volumetric mass transfer rates, reducing the footprint and costs of bioreactors while enhancing the production of biomass and hydrocarbon products, making methane conversion more economically viable and environmentally friendly.

Implementation Method 1

The development of fermentation systems that efficiently transfer gaseous substrates like methane to microbial cultures

Methodology Applied
Scientific EffectMass transfer: Diffusion

Implementation Method 2

using C1 metabolizing microorganisms such as methanotrophs and methylotrophs, within loop reactors designed for enhanced mass transfer, allowing for the conversion of methane into higher-value products

Methodology Applied
Scientific EffectFermentation: Fermentation

Data Source

PatentUS11795428B2Gas-fed fermentation reactors, systems and processes utilizing a vertical flow zone
Publication Date: 2023.10.24 CALYSTA INC
  • US11795428B2 patent drawing
  • US11795428B2 patent drawing
  • US11795428B2 patent drawing

AI summary

Reactors, systems and processes for the production of biomass by culturing microorganisms in aqueous liquid culture medium circulating in a loop reactor which utilize substantially vertical flow zones are described. Recovery and processing of the culture microorganisms to obtain products, such as proteins or hydrocarbons is described.