Vertical-Flow Sweat Sensor Using Porous Electrode Stacking

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Solution Overview

Problem

Existing chemical and biomarker sensing technologies face challenges in integrating finely patterned interdigitated electrodes with low-cost printed electronics and standard circuit board technology, and they often struggle with low analyte diffusion and transport, especially at low concentrations, due to complex fabrication and small fluid volumes.

Innovation Solution

The use of porous substrates and electrodes with easy-to-fabricate spacer materials allows for close electrode spacing and efficient analyte transport, enabling high-performance sensing with reduced diffusive path length and minimal fluid volume, suitable for integration in wearable and microfluidic devices.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If interdigitated electrodes are closely spaced to maximize sensing performance, then measurement precision is improved, but device complexity increases due to fabrication challenges

Engineering Contradiction:
Improvesensing performanceVSAvoidfabrication complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent transitions from horizontal electrode spacing to vertical stacking, allowing electrodes to be closely spaced in the vertical dimension while maintaining larger horizontal pitch compatible with standard PCB fabrication. Multiple electrode pairs are stacked vertically with spacers, achieving high sensing performance without complex horizontal patterning.

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

Solution Approach 2:

The patent uses thin substrate layers and flexible spacer structures to enable vertical stacking of electrodes. The thin-film approach allows multiple electrode pairs to be integrated in the vertical direction while maintaining compatibility with standard manufacturing processes.

Inventive Principle:
Principle #30Flexible shells and thin films

2Ease of manufacture

If horizontal flow configuration is used with porous substrates, then ease of manufacture is improved, but analyte transport to probes is reduced

Engineering Contradiction:
Improvefabrication simplicityVSAvoidanalyte transport rate
Core Design Contradiction:
Ease of manufactureVSProductivity

Solution Approach 1:

The patent changes analyte transport from horizontal flow to vertical flow through the stacked electrode structure. Analytes are delivered vertically through the porous substrate and spacer regions directly to the electrode surfaces, reducing diffusion path length and improving transport efficiency while maintaining manufacturing simplicity.

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

3Productivity

If vertical stacking with spacers is implemented, then analyte transport efficiency is improved, but device complexity increases

Engineering Contradiction:
Improveanalyte transport efficiencyVSAvoidstructural complexity
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The patent introduces spacers as intermediary elements that simultaneously perform multiple functions: maintaining vertical electrode spacing, providing analyte transport pathways, and enabling structural integration. The spacers simplify the overall design by combining support and flow functions in a single component.

Inventive Principle:
Principle #24Intermediary (Mediator)

4Volume of moving object

If small fluid volumes are used, then device miniaturization is improved, but signal-to-noise ratio deteriorates

Engineering Contradiction:
Improvefluid volumeVSAvoidsignal-to-noise ratio
Core Design Contradiction:
Volume of moving objectVSMeasurement precision

Solution Approach 1:

The patent achieves miniaturization by stacking electrodes vertically rather than expanding horizontally. This vertical integration reduces the overall device footprint and fluid volume requirements while maintaining large electrode surface areas through multiple stacked pairs, preserving signal-to-noise ratio despite reduced fluid volumes.

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach enhances signal-to-noise ratios, stabilizes sensors quickly, and facilitates easy integration with low-cost manufacturing, achieving effective detection of analytes at low concentrations with reduced fluid requirements and simplified device design.

Implementation Method 1

the low amount of diffusion or transport of analytes in flow 105 down to the probes 190

Methodology Applied
Scientific EffectDiffusion: Diffusion

Implementation Method 2

by advective flow in a fluid or gas

Methodology Applied
Scientific EffectAdvection: Advection

Implementation Method 3

Many of these techniques measure impedance or charge transfer

Methodology Applied
Scientific EffectImpedance measurement: Electrical Resistance

Implementation Method 4

measure impedance or charge transfer

Methodology Applied
Scientific EffectCharge transfer: Conduction (electrical)

Data Source

PatentEP3148415B1Vertical-flow electronic bio-chemical sensing devices
Publication Date: 2019.10.23 UNIVERSITY OF CINCINNATI
  • EP3148415B1 patent drawingFigure 1A~1B
  • EP3148415B1 patent drawingFigure 2A~2B
  • EP3148415B1 patent drawingFigure 3A~3C

AI summary

An electronic sweat sensor (300) includes a plurality of porous substrates (310, 312), each porous substrate (310, 312) having an electrically conductive surface (320, 322). The porous substrates (310, 312) have a generally planar surface. The generally planar surface may be adapted to be positioned on skin (12) generally coplanar with the skin. The electronic sweat sensor (300) further includes a porous spacer (315) layer defining a gap between at least two of the porous substrates (310, 312). When an analyte flow (305), which may be from skin (12), is moving perpendicular to the planar surface and through at least one of the porous substrates (310, 312), at least one of the conductive surfaces (320, 322) provides an electrical response to the presence of the analyte flow (305).