3D Vessel Visualization via Preoperative DSA and Intraoperative Fluorescence Overlay

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Solution Overview

Problem

Current visualization methods for vessels during medical interventions, such as 3D DSA, struggle to provide a comprehensive and up-to-date representation of blood vessels, especially in neuroradiology, as they are limited by the inability to accurately depict structures deep within the body and require multiple imaging modalities.

Innovation Solution

A method combining preoperative 3D digital subtraction angiography with intraoperative fluorescence angiography using ICG, involving 3D reconstruction, vessel identification, registration, and overlaying of images to enhance visualization, along with continuous 3D playback, utilizing a DSA X-ray system, ICG angiography device, image processing stages, and a 3D display device.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If 3D DSA rotation angiography is used for visualizing vessels, then vascular anatomy can be assessed in three dimensions, but the visualization is not up-to-date during interventions and cannot accurately depict structures deep within the body

Engineering Contradiction:
Improvevisualization accuracyVSAvoidtime lag
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The patent combines preoperative 3D DSA angiography data with intraoperative fluorescence angiography images to create a fused visualization. The 3D DSA provides anatomical structure while the intraoperative fluorescence imaging provides real-time functional information, merging two imaging modalities to achieve both accuracy and up-to-date representation during interventions

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The system performs preliminary 3D reconstruction and vessel identification using preoperative DSA data before the intervention. This preprocessed 3D vascular model serves as a reference framework that can be dynamically updated with intraoperative fluorescence images, allowing the system to maintain accurate visualization while incorporating real-time changes

Inventive Principle:
Principle #10Preliminary action

2Adaptability or versatility

If multiple imaging modalities are used to comprehensively depict vascular structures, then visualization completeness improves, but system complexity and difficulty of operation increase

Engineering Contradiction:
Improvevisualization completenessVSAvoidsystem complexity
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The system uses a unified processing platform that handles both preoperative 3D DSA data and intraoperative fluorescence images through common workflows. The same image processing, registration, and visualization infrastructure handles multiple imaging modalities, reducing overall system complexity while maintaining versatility

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The system introduces an intermediary registration and fusion module that automatically aligns 3D DSA data with 2D fluorescence images. This intermediary processing layer simplifies the integration of multiple modalities by providing automated registration based on anatomical landmarks and vessel structures, reducing the operational burden on users

Inventive Principle:
Principle #24Intermediary (Mediator)

3Measurement precision

If preoperative 3D DSA data is used for visualization, then anatomical structure is well-represented, but the data is not current during interventions when tissue may have displaced

Engineering Contradiction:
Improveanatomical representation accuracyVSAvoidcurrent accuracy
Core Design Contradiction:
Measurement precisionVSReliability

Solution Approach 1:

The system transitions from a static preoperative 3D model to a dynamic visualization that continuously incorporates intraoperative fluorescence images. The 3D DSA anatomical model serves as a starting point but is dynamically updated with real-time fluorescence data, allowing the visualization to adapt to tissue displacement and changes during the intervention while maintaining anatomical context

Inventive Principle:
Principle #15Dynamics

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach provides an enhanced, real-time visualization of blood vessels, improving upon existing methods by integrating preoperative and intraoperative data, allowing for more accurate and dynamic representation of vascular structures during procedures.

Implementation Method 1

recording at least one current 2D fluorescence image of the examination region by means of fluorescence angiography

Methodology Applied
Scientific EffectFluorescence: Fluorescence

Implementation Method 2

using a preoperatively recorded 3D image dataset of the examination region

Methodology Applied
Scientific EffectX-ray: X-Ray

Data Source

PatentUS8693758B2Imaging method for enhanced visualization of vessels in an examination region of a patient and medical system for performing the method
Publication Date: 2014.04.08 SIEMENS HEALTHINEERS AG
  • US8693758B2 patent drawing
  • US8693758B2 patent drawing
  • US8693758B2 patent drawing

AI summary

An imaging method for enhanced visualization of vessels in an examination region of a patient, in particular during an intervention, is proposed. A 3D reconstruction image of the examination region is generated using a preoperatively recorded 3D image dataset of the examination region. At least one current 2D fluorescence image of the examination region is recorded by a fluorescence angiography. The vessels are identified. The 3D image dataset with the image dataset of the 2D fluorescence or ultrasound image is registered based on the result of the identification. The 3D reconstruction image and the 2D image are overplayed. The overlaid images are 3D played back.