Noninvasive VfA Pacing Evaluation via External Electrodes

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Solution Overview

Problem

Current methods for evaluating ventricle from atrium (VfA) pacing therapy are invasive and lack noninvasive solutions for monitoring cardiac signals, making it difficult to determine acceptable pacing settings without implantable devices.

Innovation Solution

The use of external electrodes attached to the skin to noninvasively monitor electrical activity and generate paced electrical heterogeneity information, allowing for the evaluation of VfA pacing therapy without implantable devices, and adjusting pacing settings based on electrical heterogeneity metrics.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If implantable devices such as leads, probes, sensors, or catheters are used to monitor cardiac signals, then measurement precision and reliability are improved, but device complexity and invasiveness increase

Engineering Contradiction:
Improvecardiac signal monitoring accuracyVSAvoidimplantable device requirement
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent uses the patient's own body (torso) as an intermediary medium to transmit cardiac electrical signals from the heart to external electrodes on the skin surface. This eliminates the need for implantable leads and probes by utilizing the body's natural conductivity to convey cardiac information externally.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent replaces mechanical implantable devices (leads, probes, sensors, catheters) with a non-invasive electrical measurement system using external electrodes. This substitution eliminates the need for physical penetration into the body while still capturing cardiac electrical activity through surface potential differences.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

2Measurement precision

If implantable devices are used to evaluate pacing therapy, then evaluation accuracy is improved, but ease of operation and patient comfort deteriorate

Engineering Contradiction:
Improvepacing therapy evaluation accuracyVSAvoidnoninvasive evaluation capability
Core Design Contradiction:
Measurement precisionVSEase of operation

Solution Approach 1:

The system uses external electrodes placed on the skin as intermediaries to capture cardiac signals without requiring implantable devices. This allows physicians to evaluate pacing therapy accuracy and effectiveness through non-invasive surface measurements, improving patient comfort and ease of operation.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent creates an external copy of the internal cardiac electrical activity by measuring body surface potentials that replicate the heart's electrical behavior. This copied information from the surface allows accurate evaluation of pacing therapy without needing to physically access or implant devices within the heart.

Inventive Principle:
Principle #26Copying

3Reliability

If multiple paced settings are tested to determine acceptability, then reliability of therapy selection is improved, but loss of time increases

Engineering Contradiction:
Improvepaced setting selection accuracyVSAvoidevaluation time for multiple settings
Core Design Contradiction:
ReliabilityVSLoss of time

Solution Approach 1:

The system provides immediate feedback by calculating and displaying electrical heterogeneity metrics for each tested paced setting. This real-time feedback allows physicians to quickly assess multiple pacing configurations and identify acceptable settings without prolonged evaluation periods, maintaining reliability while reducing time loss.

Inventive Principle:
Principle #23Feedback

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables noninvasive evaluation of VfA pacing therapy, improving cardiac functionality assessment and allowing for optimal pacing setting determination, enhancing patient outcomes without the need for invasive procedures.

Implementation Method 1

monitoring electrical activity of a patient to determine electrical heterogeneity information associated with the patient's cardiac activity

Methodology Applied
Scientific EffectElectrical conduction through tissue: Conduction (electrical)

Data Source

PatentEP3768375B1Evaluation of ventricle from atrium pacing therapy
Publication Date: 2023.09.27 MEDTRONIC INC
  • EP3768375B1 patent drawingFigure 1
  • EP3768375B1 patent drawingFigure 2
  • EP3768375B1 patent drawingFigure 3

AI summary

Cardiac electrical heterogeneity information may be used to determine whether one or more ventricle from atrium (VfA) paced settings for VfA pacing therapy are acceptable. Cardiac electrical heterogeneity information may be generated during VfA pacing, and then evaluated to determine whether the VfA paced settings are acceptable.