Noninvasive Neuromodulation via Vibrational Energy and Feedback Control
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Solution Overview
Problem
Current noninvasive neuromodulation systems are less effective in treating movement disorders and other conditions compared to implantable devices, which require invasive surgical procedures and have associated risks.
Innovation Solution
A noninvasive treatment device comprising a vibration actuator, sensor, and controller that delivers vibrational energy based on analyzed physiological data, using AI or ML algorithms to modulate the energy delivery, thereby treating conditions like tremors without invasive procedures.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If implantable neuromodulation devices are used to treat medical conditions, then treatment efficacy is improved, but invasive surgical procedures and associated risks are introduced
Solution Approach 1:
The patent replaces the mechanical implantation system with a noninvasive external delivery system that uses magnetic fields and focused ultrasound to transmit neuromodulation signals through the skull to the brain, eliminating the need for surgical implantation while maintaining treatment efficacy
Solution Approach 2:
The patent introduces magnetic fields and focused ultrasound as intermediary carriers to transmit neuromodulation signals noninvasively through the skull to the target brain regions, serving as a mediator between the external device and the neurological tissue
2Object-affected harmful factors
If noninvasive neuromodulation systems are used to avoid surgical risks, then surgical risks are reduced, but treatment efficacy decreases
Solution Approach 1:
The patent employs parameter changes in the form of varying magnetic field strengths and focused ultrasound frequencies to optimize signal transmission through the skull, enabling effective neuromodulation without surgery by adjusting physical parameters of the delivery mechanism
Solution Approach 2:
The patent uses periodic pulsed delivery of magnetic fields and focused ultrasound waves to stimulate neurological tissue, employing rhythmic on-off cycles that mimic natural brain wave patterns and enhance treatment efficacy through temporal modulation
3Measurement precision
If continuous monitoring and adjustment of vibrational energy is implemented, then treatment precision is improved, but device complexity increases
Solution Approach 1:
The patent implements feedback control by continuously monitoring patient response to vibrational stimulation and automatically adjusting the intensity and frequency of the stimulus, creating a closed-loop system that enhances treatment precision through real-time adaptation
Solution Approach 2:
The patent enables the device to self-regulate by using built-in sensors to monitor treatment effects and automatically adjust parameters without requiring constant external intervention, allowing the system to serve itself in optimizing treatment delivery
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The system effectively treats conditions like tremors by delivering targeted vibrational energy, improving treatment efficacy while avoiding the risks associated with invasive surgical procedures.
Implementation Method 1
a vibration actuator configured to deliver vibrational energy to a treatment site of a user
Data Source
AI summary
Noninvasive treatment (e.g., neuromodulation) can be achieved using vibrational energy applied via one or more wearable devices. A noninvasive treatment device includes a vibrational actuator disposed within a housing that can be secured to a user's body at or adjacent a treatment site. One or more sensors can collect physiological data before, during, or after application of vibrational energy to monitor a user's condition. Machine learning or other suitable approaches can be used to analyze sensor data to detect medical conditions and/or to effect treatment of medical conditions using devices as described herein.