Vibrational Wire Guide for Chronic Venous Clot Penetration

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Solution Overview

Problem

Conventional interventional techniques are ineffective in treating chronic venous clots due to their hardening, which makes it difficult for guidewires to penetrate and cross, hindering the introduction of treatment devices.

Innovation Solution

A non-rotatable wire guide with a specially designed cutting head, utilizing ultrasonic vibrational movement to penetrate and core through chronic clots, creating a passageway for inserting a guidewire without rotating, and featuring a concave proximal end and convex distal end with blades or grooves for effective cutting.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If conventional guidewires are used to penetrate chronic clots, then the procedure should be simple, but the hardening of chronic clots prevents guidewire penetration and crossing

Engineering Contradiction:
Improveguidewire penetration capabilityVSAvoidclot hardness
Core Design Contradiction:
ReliabilityVSStrength

Solution Approach 1:

The cutting head is equipped with ultrasonic vibrational elements that generate high-frequency mechanical vibrations to cut through the hardened chronic clot material. The vibrations enable the cutting head to penetrate and core through the crosslinked collagen structure that conventional guidewires cannot penetrate.

Inventive Principle:
Principle #18Mechanical vibration

Solution Approach 2:

The patent replaces the simple mechanical pushing action of conventional guidewires with an ultrasonic vibration-based cutting mechanism. This substitution allows the system to effectively interact with and cut through the hardened clot material by converting mechanical energy into vibrational energy at ultrasonic frequencies.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

2Reliability

If a cutting head is added to enable clot penetration, then penetration capability improves, but device complexity increases

Engineering Contradiction:
Improveclot penetration capabilityVSAvoidwire guide structure
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The cutting head is designed to perform multiple functions: it can rotate to cut through the clot, it can translate axially to penetrate the obstruction, and it can be withdrawn to core out the clot material. This multi-functionality consolidates several operations into a single device component, managing complexity while enhancing capability.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The cutting head is positioned within the wire guide shaft, and the entire assembly is introduced through a catheter system. This nested configuration allows the complex cutting mechanism to be delivered through standard vascular access routes, managing the complexity of the cutting mechanism while maintaining compatibility with existing delivery systems.

Inventive Principle:
Principle #7Nested doll (Nesting)

3Productivity

If rotation is allowed for cutting, then cutting efficiency improves, but the wire guide may rotate uncontrollably in the vessel

Engineering Contradiction:
Improvecutting speedVSAvoidwire guide stability
Core Design Contradiction:
ProductivityVSEase of operation

Solution Approach 1:

The cutting head's rotation is made conditional and dynamic rather than continuous. Rotation is engaged only when needed for cutting through the clot, and the system can switch between rotational cutting mode and axial translation mode. This dynamic control allows efficient cutting while maintaining stability when rotation is not active.

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The system incorporates control mechanisms that monitor the cutting head's position and rotational state, allowing the operator to engage or disengage rotation as needed. This feedback-based control prevents uncontrolled rotation while enabling efficient cutting when required, balancing productivity with operational stability.

Inventive Principle:
Principle #23Feedback

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables the creation of a lumen through chronic clots, allowing for the insertion of guidewires and facilitating treatment by effectively cutting through the hardened clot using ultrasonic energy and axial translation without rotation.

Implementation Method 1

utilizing ultrasonic vibrational movement to penetrate and core through chronic clots

Methodology Applied
Scientific EffectUltrasonic vibration: Ultrasonic Vibration

Data Source

PatentEP4076222B1Vibrational wire guide for coring and aspirating a venous obstruction
Publication Date: 2024.05.22 KONINKLIJKE PHILIPS NV
  • EP4076222B1 patent drawingFigure 1
  • EP4076222B1 patent drawingFigure 2
  • EP4076222B1 patent drawingFigure 3

AI summary

The present disclosure relates generally to medical devices and the use of medical devices for the treatment of vascular conditions. Particularly, the present disclosure provides devices and methods for using a vibrational wire guide to cut and/or core through a venous obstruction, such as a chronic clot.